5 children (aged 4-12) who traveled to or from Pakistan during late 2017 through mid-2018 have been diagnosed in the US with extensively drug-resistant (XDR) typhoid infectious
The outbreak in Pakistan involves a Salmonella enterica serotype Typhi strain that is resistant to most antibiotics commonly used to treat the illness
Between November 2016 and September 2017, 339 infections caused by the XDR Typhi strain were reported in Pakistan, with one travel-related case also reported in the United Kingdom. Enhanced surveillance efforts in Pakistan identified a total of 5,372 cases as of Dec. 30