Single Dose of New Typhoid Vaccine Protects Kids Long-Term

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  • Typbar TCV, a one-shot vaccine, shows promise in providing long-term protection against typhoid in children aged 9 months to 12 years.
  • A four-year study in Malawi involving over 28,000 children demonstrates a more than 78% efficacy rate for the TCV vaccine. Rates of typhoid incidence dramatically decrease among children who receive the TCV shot.
  • The trial’s success leads the Malawi government to commit to vaccinating all children under 15, with babies receiving the Typbar TCV shot at 9 months as part of routine vaccinations.
  • The results come at a critical time when climate change, extreme weather events, and increased urbanization may contribute to the rise of enteric diseases, including typhoid.