Does a typhoid vaccine protect against multiple threats?

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  • A recent study investigated the protective effects of a typhoid vaccine against microbes that are not the target of prevention.
  • Analysis of immune system cells called monocytes revealed their activation in vaccinated individuals for a period of over three months after vaccination.
  • This analysis showed that white blood cells from vaccinated individuals initiated a response against microbes unrelated to typhoid fever by producing specific cytokines, which are messenger molecules of the immune system.