- Treatment-resistant typhoid originating mostly from South Asia has springboarded across borders almost 200 times in the past three decades, according to new research that underscores the increasing global threat of infections that can evade antibiotics.
- The findings, published in The Lancet Microbe, showed that while resistance to first-line treatments generally declined across South Asia, global issues remained. The number of strains able to overpower macrolides and quinolones, two important types of antibiotics, climbed sharply and frequently spread to other countries, the study found.
- The findings are “a real cause for concern,” said Jason Andrews, an associate professor at Stanford University and the study’s lead author, urging that prevention measures be put in place, particularly in high-risk nations. “The fact resistant strains of S. Typhi have spread internationally so many times also underscores the need to view typhoid control, and antibiotic resistance more generally, as a global rather than local problem”.
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