West Nile virus infection in suspected febrile typhoid cases in Xinjiang, China

AUTHORS

Lei Cao, Shihong Fu, Zhi Lv, Chengjun Tang, Shiheng Cui, Xiaolong Li, Xiaoyan Gao, Minghua Li, Yuxi Cao, Wenwen Lei, Ying He, Huanyu Wang and Guodong Liang

ABSTRACT

West Nile virus (WNV) is a mosquito-borne virus. Infection with WNV generally causes a self-limiting disease, with central nervous system symptoms in severe cases. As the discovery of encephalitis caused by WNV in the United States in 1999, the virus has become a serious public health concern and a global emerging infectious disease. However, most WNV-infected patients have only a transient fever with mild clinical manifestations, especially during the early stages of infection, which can easily be overlooked by clinicians and patients. Typhoid fever is an infectious intestinal disease caused by the bacterium Salmonella typhi. Severe cases may show numerous clinical manifestations, including rose-colored spots on the abdomen and hepatosplenomegaly. As with other acute infectious diseases, a high-grade fever may occur during the early stage of the disease; this can easily lead to misdiagnoses of these acute infectious diseases.

Click here to view the article, published in Nature.