AUTHORS
Alireza Eshaghi, Sandra Zittermann, Amrita Bharat, Michael R Mulvey, Vanessa G Allen, Samir N Patel
ABSTRACT
A strain of extensively drug-resistant (XDR) Salmonella enterica serovar Typhi has caused a large ongoing outbreak in Pakistan since 2016. In Ontario, Canada, 10 cases of mainly bloodstream infections (n = 9) were identified in patients who traveled to Pakistan. Whole-genome sequencing showed that Canadian cases were genetically related to the Pakistan outbreak strain. The appearance of XDR typhoid cases in Ontario prompted a provincial wide alert to physicians to recommend treatment with carbapenems or azithromycin in suspected typhoid cases with travel history to Pakistan.
Click here to read the article, published in the American Society for Microbiology.
