Early Insights From Clinical Trials of Typhoid Conjugate Vaccine

AUTHORS

Kathleen M Neuzil, Buddha Basnyat, John D Clemens, Melita A Gordon, Priyanka D Patel, Andrew J Pollard, Mila Shakya, Firdausi Qadri

ABSTRACT

Clinical trials of typhoid conjugate vaccine (TCV) are ongoing in 4 countries. Early data confirm safety, tolerability, and immunogenicity of typhoid conjugate vaccine, and early efficacy results are promising. These data support World Health Organization recommendations and planned country introductions. Forthcoming trial data will continue to inform programmatic use of typhoid conjugate vaccine.

Click here to read the article, published in Clinical Infectious Diseases.