New data from research on the disease burden of typhoid and ways to prevent, treat, and control the disease are crucial in the fight to take on typhoid. See the latest key publications or filter and search the full list of typhoid publications below.
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Prospects of future typhoid and paratyphoid vaccines in endemic countries
AUTHORS Mila Shakya, Kathleen M Neuzil, Andrew J Pollard ABSTRACT Low- and middle-income countries face a high burden of typhoid and paratyphoid fever due to poor water quality and inadequate ...
Read moreAnalysis of 56,348 Genomes Identifies the Relationship between Antibiotic and Metal Resistance and the Spread of Multidrug-Resistant Non-Typhoidal Salmonella
AUTHORS Gavin J Fenske, Joy Scaria ABSTRACT Salmonella enterica is common foodborne pathogen that generates both enteric and systemic infections in hosts. Antibiotic resistance is common is certain serovars of the pathogen ...
Read moreEffectiveness of typhoid conjugate vaccine against culture-confirmed Salmonella enterica serotype Typhi in an extensively drug-resistant outbreak setting of Hyderabad, Pakistan: a cohort study
AUTHORS Mohammad Tahir Yousafzai, Sultan Karim, Sonia Qureshi, Momin Kazi, Hina Memon, Amber Junejo, Zohra Khawaja, Najeeb Ur Rehman, Muhammad Sajid Ansari, Rafey Ali, Ikram Uddin Ujjan, Heera Mani Lohana, Naveed M Memon, Mudassar Hussain, Roohi Nigar, Naor Bar-Zeev, Farah Naz Qamar ABSTRACT Background: Salmonella enterica serotype ...
Read moreRisk of non-typhoidal Salmonella vascular infections is increased with degree of atherosclerosis and inflammation: A multicenter study in southern Taiwan
AUTHORS Ying-Wen Chen, Hung-Jen Tang, Yi-Shan Tsai, Nan-Yao Lee, Yuan-Pin Hung, Chien-Fang Huang, Ching-Chi Lee, Chia-Wen Li, Ming-Chi Li, Ling-Shan Syue, Shu-Li Su, Shu-Hao Hsu, Wen-Chien Ko, Po-Lin Chen ABSTRACT Background: Atherosclerosis and vascular inflammatory response have been considered as risk factors for non-typhoidal ...
Read moreBactericidal activities and post-antibiotic effects of ofloxacin and ceftriaxone against drug-resistant Salmonella enterica serovar Typhi
AUTHORS John Wain, Julie A Simpson, Thi Diem Nga Luong, Song Diep To, Thanh Duy Pham, Stephen Baker, Nicholas P J Day, Nicholas J White, Christopher M Parry ABSTRACT Background: The clinical response to ceftriaxone in patients with ...
Read moreNon-Typhoidal Salmonella and the Risk of Kawasaki Disease: A Nationwide Population-Based Cohort Study
AUTHORS Thomas Yen-Ting Chen, Mei-Chia Chou, Jung-Nien Lai, Lu-Ting Chiu, Renin Chang, Yao-Min Hung, James Cheng-Chung Wei ABSTRACT Objective: The aim of this study was to investigate the relationship between non-typhoidal Salmonella (NTS) infection and the risk of Kawasaki ...
Read moreThe emergence of azithromycin-resistant Salmonella Typhi in Nepal
AUTHORS Pham Thanh Duy, Sabina Dongol, Abhishek Giri, Nguyen Thi Nguyen To, Ho Ngoc Dan Thanh, Nguyen Pham Nhu Quynh, Pham Duc Trung, Guy E Thwaites, Buddha Basnyat, Stephen Baker, Maia A Rabaa, Abhilasha Karkey ABSTRACT Background: Typhoid fever remains a significant ...
Read moreOpen Label Randomized Controlled Comparison of Three Alternative Regimes of Ciprofloxacin, Azithromycin and Cefixime for Treatment of Uncomplicated Typhoid Fever in Bangladesh
AUTHORS M R Amin, S K Das, A Kabir, M R Islam, S M Ahmed, M J Hasan ABSTRACT Multi-drug resistant Typhoid fever (resistant to previously used chloramphenicol, ampicillin, amoxicillin, and trimethoprim-sulfamethoxazole) has been commonly ...
Read moreSalmonella Paratyphi Infection: Use of Nanopore Sequencing as a Vivid Alternative for the Identification of Invading Bacteria
AUTHORS Martin Chmel, Oldřich Bartoš, Ondřej Beran, Petr Pajer, Jiří Dresler, Martina Čurdová, Michal Holub ABSTRACT In our study we present an overview of the use of Oxford Nanopore Technologies (ONT) sequencing technology on the background ...
Read moreTyphoid fever presenting as acute psychosis in a young adult: case report and literature review of typhoid psychosis
AUTHORS H Esa, B Norazlah, A A Hameed, C H Ding, A A Wahab ABSTRACT The rarity of acute psychosis in typhoid fever can result in delayed and misdiagnosis of the condition. We report ...
Read moreCost effectiveness of typhoid vaccination in India
AUTHORS Akashdeep Singh Chauhan, Isha Kapoor, Saroj Kumar Rana, Dilesh Kumar, Madhu Gupta, Jacob John, Gagandeep Kang, Shankar Prinja ABSTRACT Introduction: World Health Organization has prequalified the use of typhoid conjugate vaccine (TCV) in children over six months ...
Read moreAntimicrobial sensitivity patterns of enteric fever in Pakistan: a comparison of years 2009 and 2019
AUTHORS Khurram Saleem, Sana Zafar, Aqeela Rashid ABSTRACT Background: Pakistan is one of the endemic regions for typhoid fever and paratyphoid fever. This study aimed to identify the evolving antimicrobial sensitivity patterns of ...
Read moreSingle cell analyses reveal distinct adaptation of typhoidal and non-typhoidal Salmonella enterica serovars to intracellular lifestyle
AUTHORS Tatjana Reuter, Felix Scharte, Rico Franzkoch, Viktoria Liss, Michael Hensel ABSTRACT Salmonella enterica is a common foodborne, facultative intracellular enteropathogen. Human-restricted typhoidal S. enterica serovars Typhi (STY) or Paratyphi A (SPA) cause severe ...
Read moreIncreased non-typhoidal Salmonella hospitalizations in transfusion-naïve thalassemia children: a nationwide population-based cohort study
AUTHORS Fang-Ju Lin, Jiunn-Ming Sheen, Yao-Hsu Yang, Kuang-Che Kuo ABSTRACT Introduction: Although non-typhoidal Salmonella (NTS) infection usually causes self-limited enterocolitis, several risk factors have been found to predispose individuals to more severe NTS infections. ...
Read moreRapid detection of ceftriaxone resistance in clinical isolates of extensively drug resistant Salmonella enterica serovar Typhi
AUTHORS Muhammad Luqman Satti, Faisal Hanif, Ashfaq Hussain, Saman Nadeem, Faryal Younis, Nadia Midhat Zehra ABSTRACT Objective: To see the efficacy of rapid colour test for the sensitivity of ceftriaxone against clinical isolates of salmonella typhi. ...
Read moreMechanisms of typhoid toxin neutralization by antibodies targeting glycan receptor binding and nuclease subunits
AUTHORS Changhwan Ahn, Yi-An Yang, Durga P Neupane, Tri Nguyen, Angelene F Richards, Ji Hyun Sim, Nicholas J Mantis, Jeongmin Song ABSTRACT Nearly all clinical isolates of Salmonella Typhi, the cause of typhoid fever, ...
Read moreAn Outer Membrane Vesicle-Adjuvanted Oral Vaccine Protects Against Lethal, Oral Salmonella Infection
AUTHORS Jaikin E Harrell, Jonathan R Kurtz, David L Bauer, J Timothy Prior, Patrick S Gellings, Lisa A Morici, James B McLachlan ABSTRACT Non-typhoidal salmonellosis, caused by Salmonella enterica serovar Typhimurium is a common fecal-oral disease characterized ...
Read morePresence of plasmid-mediated quinolone resistance (PMQR) genes in non-typhoidal Salmonella strains with reduced susceptibility to fluoroquinolones…in Gyeonggi-do, South Korea from 2016 to 2019
AUTHORS Sohyun Lee, Nanjoo Park, Sujung Yun, Eunseon Hur, Jiwon Song, Hanna Lee, Yongsug Kim, Sangryeol Ryu ABSTRACT Non-typhoidal salmonellosis remains a pressing public health problem worldwide. Quinolones, particularly fluoroquinolones, are widely used to treat various infections, ...
Read moreSafety and immunogenicity of Vi-typhoid conjugate vaccine co-administration with routine 9-month vaccination in Burkina Faso: A randomised controlled phase 2 trial
AUTHORS Sodiomon B Sirima, Alphonse Ouedraogo, Nouhoun Barry, Mohamadou Siribie, Alfred Tiono, Issa Nébié, Amadou Konaté, Gloria Damoaliga Berges, Amidou Diarra, Moussa Ouedraogo, Edith C Bougouma, Issiaka Soulama, Alimatou Hema, Shrimati Datta, Yuanyuan Liang, Elizabeth T Rotrosen, J Kathleen Tracy, Leslie P Jamka, Jennifer J Oshinsky, Marcela F Pasetti, Kathleen ...
Read moreGeographical distribution of risk factors for invasive non-typhoidal Salmonella at the subnational boundary level in sub-Saharan Africa
AUTHORS Jung-Seok Lee, Vittal Mogasale, Florian Marks, Jerome Kim ABSTRACT Background: Invasive non-typhoidal Salmonella (iNTS) is a growing health-concern in many parts of sub-Saharan Africa. iNTS is associated with fatal diseases such as HIV ...
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