New data from research on the disease burden of typhoid and ways to prevent, treat, and control the disease are crucial in the fight to take on typhoid. See the latest key publications or filter and search the full list of typhoid publications below.
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Development of a live attenuated bivalent oral vaccine against Shigella sonnei shigellosis and typhoid fever
AUTHORS Wu Y., Chakravarty S., Li M., Wai T.T., Hoffman S.L., Sim BK. ABSTRACT Shigella sonnei (Ss) and Salmonella Typhi cause significant morbidity and mortality. We exploited the safety record ...
Read moreRefusal of recommended travel-related vaccines among U.S. international travellers in Global TravEpiNet
AUTHORS Lammert SM, Rao SR, Jentes ES, Fairley JK, Erskine S, Walker AT, Hagmann SH, Sotir MJ, Ryan ET, LaRocque RC. ABSTRACT BACKGROUND: International travellers are at risk of travel-related, ...
Read moreThe unrecognized burden of typhoid fever
AUTHORS Obaro, Stephen; Tam, Pui-Ying Iroh; Mintz, Eric Daniel. ABSTRACT Introduction: Typhoid fever (TF), caused by Salmonella enterica serovar Typhi, is the most common cause of enteric fever, responsible for ...
Read moreThe tolerability of a combined hepatitis A and typhoid vaccine in children aged 2-16 years: an observational study
AUTHORS Lau, CL; Streeton, CL; David, MC; Sly, PD; Mills, DJ. ABSTRACT BACKGROUND: Combined hepatitis A and typhoid vaccines have been widely used globally and proven to be safe, well tolerated and efficacious in ...
Read morePurification of Salmonella Typhimurium OmpD porin induces long-term high levels of antibodies: implications on the development of vaccines against non-typhoid salmonella
AUTHORS Pérez-Toledo, M.; Martínez-Amador, P.A.; Pastelin-Palacios, R.; Isibasi, A.; Cunningham, A.F.; & López-Macías, C. ABSTRACT In the present work, we report, for the first time, on the purification of the Salmonella Typhimurium OmpD porin. ...
Read moreTyphoid Fever in South Africa in an Endemic HIV Setting
AUTHORS Keddy KH.; Sooka, A.; Smith, AM.; Musekiwa, A.; Tau, NP.; Klugman, KP.; Angulo, FJ. ABSTRACT BACKGROUND: Typhoid fever remains an important disease in Africa, associated with outbreaks and the ...
Read moreSalmonella enterica serovar Typhi and gallbladder cancer: a case-control study and meta-analysis
AUTHORS Koshiol J., et al ABSTRACT In Chile, where gallbladder cancer (GBC) rates are high and typhoid fever was endemic until the 1990s, we evaluated the association between Salmonella enterica ...
Read moreA prospective study of the importance of enteric fever as a cause of non-malarial febrile illness in patients admitted to Chittagong Medical College Hospital, Bangladesh
AUTHORS Maude, RR., et al ABSTRACT BACKGROUND: Fever is a common cause of hospital admission in Bangladesh but causative agents, other than malaria, are not routinely investigated. Enteric fever is ...
Read moreAn extended genotyping framework for Salmonella enterica serovar Typhi, the cause of human typhoid
AUTHORS Wong, VK, et al ABSTRACT The population of Salmonella enterica serovar Typhi (S. Typhi), the causative agent of typhoid fever, exhibits limited DNA sequence variation, which complicates efforts to ...
Read moreEpidemiological investigation of an outbreak of typhoid fever in Jorhat town of Assam, India
AUTHORS Roy JS, Saikia L, Medhi M, Tassa D ABSTRACT BACKGROUND & OBJECTIVES: Typhoid fever is a global health problem and is also endemic in India. An outbreak of fever ...
Read moreDisseminated infections with antibiotic-resistant non-typhoidal Salmonella strains: contributions of host and pathogen factors
AUTHORS Lokken, KL.; Walker, GT.; Tsolis, RM. ABSTRACT Non-typhoidal Salmonella enterica serovars (NTS) are generally associated with gastroenteritis; however, the very young and elderly, as well as individuals with compromised ...
Read moreEvaluation of medicine retail outlets for sale of typhoid fever vaccine among adults in two urban and rural settings in western Kenya: a proof-of-concept study
AUTHORS Ho, J., et al ABSTRACT BACKGROUND: Private sector medicine outlets are an important provider of health services across the developing world, and are an untapped means of distributing and ...
Read moreDevelopment of an Acid-Resistant Salmonella Typhi Ty21a Attenuated Vector For Improved Oral Vaccine Delivery
AUTHORS Dharmasena MN, Feuille CM, Starke CE, Bhagwat AA, Stibitz S, & Kopecko DJ ABSTRACT The licensed oral, live-attenuated bacterial vaccine for typhoid fever, Salmonella enterica serovar Typhi strain Ty21a, ...
Read moreGyrA ser83 and ParC trp106 Mutations in Salmonella enterica Serovar Typhi Isolated from Typhoid Fever Patients in Tertiary Care Hospital
AUTHORS Gopal M.; Elumalai, S.; Arumugam, S.; Durairajpandian, V.; Kannan, MA.; Selvam, E.; & Seetharam, S.; ABSTRACT INTRODUCTION: Typhoid fever is endemic in India and other developing countries, causing major ...
Read moreRab32 restriction of intracellular bacterial pathogens
AUTHORS Solano-Collado, V.; Rofe, A.; & Spano, S. ABSTRACT Our immune system is engaged in a continuous battle against invading pathogens, many of which have evolved to survive in intracellular ...
Read moreTyphoidal Salmonellae: Use of Multi-Locus Sequence Typing to Determine Population Structure
AUTHORS Sharma, P.; et al ABSTRACT Enteric fever is an invasive infection predominantly caused by Salmonella enterica serovars Typhi and Paratyphi A. The pathogens have evolved from other nontyphoidal salmonellaeto ...
Read moreCross-reactive multifunctional CD4+ T cell responses against Salmonella enterica serovars Typhi, Paratyphi A and Paratyphi B in humans following immunization with live oral typhoid vaccine Ty21a
AUTHORS Wahid, R.; Fresnay, S.; Levine, MM.; & Sztein, MB. ABSTRACT The live oral typhoid vaccine Ty21a elicits predominantly CD8+, as well as CD4+ T cells mediated immune responses.Clinical field ...
Read moreGeographical and temporal trends in imported infections from the tropics requiring inpatient care at the Hospital for Tropical Diseases, London – a 15 year study
AUTHORS Marks, M.; Armstrong, M.; Whitty, CJ.; and Doherty, JF. ABSTRACT INTRODUCTION: Understanding geographic and temporal trends in imported infections is key to the management of unwell travellers. Many tropical ...
Read moreAntimicrobial susceptibility pattern and sequence analysis of DNA gyrase and DNA topoisomerase IV in Salmonella enterica serovars Typhi and Paratyphi A isolates with decreased susceptibility to ciprofloxacin
AUTHORS Misra, R.; Thakare, R.; Amrin, N.; Prasad, KN.; Chopra, S.; & Dhole, TN. ABSTRACT BACKGROUND: We describe the antimicrobial susceptibility pattern of 100 typhoidal Salmonella isolates recovered from blood ...
Read moreA magneto-DNA nanoparticle system for the rapid and sensitive diagnosis of enteric fever
AUTHORS Park, KS.; et al ABSTRACT There is currently no widely available optimal assay for diagnosing patients with enteric fever. Here we present a novel assay designed to detect amplified ...
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