New data from research on the disease burden of typhoid and ways to prevent, treat, and control the disease are crucial in the fight to take on typhoid. See the latest key publications or filter and search the full list of typhoid publications below.
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How patients navigate the diagnostic ecosystem in a fragmented health system: a qualitative study from India
AUTHORS Vijayashree Yellapa, Narayanan Devadasan, Anja Krumeich, Nitika Pant Pai, Caroline Vadnais, Madhukar Pai and Nora Engel ABSTRACT BACKGROUND: Depending on a country’s diagnostic infrastructure, patients and providers play different roles in ensuring that correct and ...
Read moreAssessment of Fecal Exposure Pathways in Low-Income Urban Neighborhoods in Accra, Ghana: Rationale, Design, Methods, and Key Findings of the SaniPath Study
AUTHORS Katharine Robb, Clair Null, Peter Teunis, Habib Yakubu, George Armah, and Christine L. Moe ABSTRACT Rapid urbanization has contributed to an urban sanitation crisis in low-income countries. Residents in low-income, ...
Read moreSalmonella enterica serovar-specific transcriptional reprogramming of infected cells
AUTHORS Hannemann S, Galán JE ABSTRACT Despite their high degree of genomic similarity, different Salmonella enterica serovars are often associated with very different clinical presentations. In humans, for example, the ...
Read moreA recombinant protein of Salmonella Typhi induces humoral and cell-mediated immune responses including memory responses
AUTHORS Das S, Chowdhury R, Ghosh S, Das S ABSTRACT Gram negative enteric bacteria, Salmonella enterica serovar Typhi (S. Typhi), the etiological agent of typhoid fever is a major public ...
Read moreFirst characterization of immunogenic conjugates of Vi negative Salmonella Typhi O-specific polysaccharides with rEPA protein for vaccine development
AUTHORS Salman M, St Michael F, Ali A, Jabbar A, Cairns C, Hayes AC, Rahman M, Iqbal M, Haque A, Cox AD ABSTRACT Efficacious typhoid vaccines for young children will ...
Read moreA cross-sectional seroepidemiological survey of typhoid fever in Fiji
AUTHORS Watson CH, Baker S, Lau CL, Rawalai K, Taufa M, Coriakula J, Thieu NTV, Van TT, Ngoc DTT, Hens N, Lowry J, de Alwis R, Cano J, Jenkins K, ...
Read moreEstimation of the probability of bacterial population survival: Development of a probability model to describe the variability in time to inactivation of Salmonella enterica
AUTHORS Kento Koyama, Hidekazu Hokunan, Mayumi Hasegawa, Shigenobu Koseki ABSTRACT Despite the development of numerous predictive microbial inactivation models, a model focusing on the variability in time to inactivation for ...
Read moreGallbladder sludge associated with ceftriaxone therapy for typhoid fever in Nigerian children: A case series
AUTHORS Hafsatu W Idris, Lawal W Umar, Sakina Abdullahi, Ahmed U Hamidu ABSTRACT Ceftriaxone is a third-generation cephalosporin with a wide spectrum of activity against both gram-negative and gram-positive organisms. ...
Read morePopulation-based incidence, seasonality and serotype distribution of invasive salmonellosis among children in Nanoro, rural Burkina Faso
AUTHORS Guiraud I, Post A, Diallo SN, Lompo P, Maltha J, Thriemer K, Tahita CM, Ley B, Derra K, Bottieau E, Kazienga A, Schurmans C, Ravinetto R, Rouamba E, Van Griensven J, Bertrand S, Tinto H, Jacobs J ABSTRACT BACKGROUND: Bloodstream infections (BSI) caused by Salmonella Typhi and invasive ...
Read moreDEATH AND THE MEDIA: INFECTIOUS DISEASE REPORTING DURING THE HEALTH TRANSITION
AUTHORS Costa DL, Kahn ME ABSTRACT In the late 19th Century, cities in Western Europe and the United States suffered from high levels of infectious disease. Over a 40 year period, ...
Read moreChronic active parietal osteomyelitis due to Salmonella typhi in a patient with Sickle Cell Anemia
AUTHORS Ahmad Antar, George Karam, Maurice Kfoury, Nadim El- Majzoub ABSTRACT Sickle cell disease (SCD) is a genetic disorder characterized by a marked heterogeneity in clinical and hematologic severity, with ...
Read moreMolecular Subtyping of Salmonella enterica Serovar Typhi by Pulsed-Field Gel Electrophoresis and Multiple-Locus Variable-Number Tandem-Repeat Analysis in India: Their Association with Antimicrobial Resistance Profiles
AUTHORS Das S, Samajpati S, Roy I, Sankar S, Gaind R, Deb M, Kulkarni R, Kumar Paul D, Dutta S ABSTRACT Molecular subtyping, and recently DNA sequencing based methods, which are commonly used for discriminating Salmonella enterica serovar ...
Read moreThe STRATAA study protocol: a programme to assess the burden of enteric fever in Bangladesh, Malawi and Nepal using prospective population census, passive surveillance, serological studies and healthcare utilisation surveys
AUTHORS Darton TC, Meiring JE, Tonks S, Khan MA, Khanam F, Shakya M, Thindwa D, Baker S, Basnyat B, Clemens JD, Dougan G, Dolecek C, Dunstan SJ, Gordon MA, Heyderman RS, Holt KE, Pitzer VE, Qadri F, Zaman K, Pollard AJ; STRATAA Study Consortium ABSTRACT INTRODUCTION: Invasive infections caused by Salmonella ...
Read moreSpecific and cross-reactive plasmablast response in humans after primary and secondary immunization with Vi capsular polysaccharide typhoid vaccine
AUTHORS Pakkanen SH, Kantele JM, Rombo L, Kantele A ABSTRACT Secondary immunization with polysaccharide vaccines may imply a risk of hyporesponsiveness. Despite the wide use of typhoid Vi capsular polysaccharide vaccine, its potential tendency to ...
Read moreClean water, clean hands or new vaccines?
AUTHORS Stephen P. Luby ABSTRACT Throughout human history, pathogens transmitted through feces from person to person have caused substantial mortality. Over a century ago civil engineers in high income countries ...
Read moreDevelopment of ELISAs for diagnosis of acute typhoid fever in Nigerian children
AUTHORS Jiin Felgner, Aarti Jain, Rie Nakajima, Li Liang, Algis Jasinskas, Eduardo Gotuzzo, Joseph M. Vinetz, Fabio Miyajima, Munir Pirmohamed, Fatimah Hassan-Hanga, Dominic Umoru, Binta Wudil Jibir, Safiya Gambo, Kudirat ...
Read moreIn vitro efficacy and in-silico analysis of cefixime-ofloxacin combination for Salmonella Typhi from bloodstream infection
AUTHORS Bakthavatchalam YD, D TK, Tayubi IA, S BA, Babu P, Munusamy E, Thukkaram B, Ravi R, Doss C GP, Veeraraghavan B ABSTRACT Recently, the cefixime-ofloxacin combination is approved by drug controller general of India (DCGI) to treat typhoid fever. ...
Read moreMolecular dynamics approach to probe the antigenicity of PagN – an outer membrane protein of Salmonella Typhi
AUTHORS Goswami N, Hussain MI, Borah P ABSTRACT PagN is a highly immunogenic 27-kDa outer membrane adhesin present in Salmonella Typhi. It plays a major role in the pathogenesis of ...
Read moreProtection against inhalation anthrax by immunization with Salmonella enterica serovar Typhi Ty21a stably producing protective antigen of Bacillus anthracis
AUTHORS B. Kim Lee Sim, Minglin Li, Manuel Osorio, Yun Wu, Tint T. Wai, Johnny W. Peterson, Eric R. James, Sumana Chakravarty, Lixin Gao, Rui Xu, Natasha KC, Richard E. ...
Read moreSynthesis and Antigenic Evaluation of Oligosaccharide Mimics of Vi Antigen from Salmonella typhi
AUTHORS Ye X, Zhang GL, Yang L, Zhu J ABSTRACT Salmonella typhi is responsible for typhoid fever, which is a serious health threat in developing countries. As a virulent factor ...
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