New data from research on the disease burden of typhoid and ways to prevent, treat, and control the disease are crucial in the fight to take on typhoid. See the latest key publications or filter and search the full list of typhoid publications below.
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Ceftriaxone-resistant Salmonella Typhi Outbreak in Hyderabad City of Sindh, Pakistan: High Time for the Introduction of Typhoid Conjugate Vaccine
AUTHORS Mohammad Tahir Yousafzai, Farah Naz Qamar, Sadia Shakoor, Khalid Saleem, Heeramani Lohana, Sultan Karim, Aneeta Hotwani, Shahida Qureshi, Naveed Masood, Mudasir Rauf, Jamshed Ahmed Khanzada, Momin Kazi, and Rumina ...
Read moreMultidrug-resistant Nontyphoidal Salmonella Hotspots as Targets for Vaccine Use in Management of Infections in Endemic Settings
AUTHORS Samuel Kariuki, Cecilia Mbae, Robert Onsare, Susan M Kavai, Celestine Wairimu, Ronald Ngetich, Mohammad Ali, John Clemens, and Gordon Dougan Background Salmonella infections cause a disproportionately high number of ...
Read moreIntroduction of Typhoid Conjugate Vaccines in Africa and Asia
AUTHORS Kathleen M Neuzil, Andrew J Pollard, and Anthony A Marfin ABSTRACT Typhoid fever continues to be a major public health concern, particularly in many low- and middle-income countries. The ...
Read moreIntegrating Typhoid Fever Within the Sustainable Development Goals: Pragmatism or Utopia?
AUTHORS Zulfiqar A Bhutta ABSTRACT Several decades following the first estimates of the global burden of typhoidal salmonellosis (infections caused by Salmonella Typhi and Salmonella Paratyphi), this disorder remains a ...
Read moreTrends in antibiotic susceptibility of enteric fever isolates from South India, 2002–2013
AUTHORS Sangeeta Joshi, Ranjeeta Adhikary, Hosdurg Bhaskar Beena, Malavalli Venkatesh Bhavana, and Air Vice Mshl Rajvir Bhalwar (Retd) ABSTRACT Enteric fever is endemic in India. Trends in antibiotic resistance in ...
Read moreStructural and Physiological Exploration of Salmonella Typhi YfdX Uncovers Its Dual Function in Bacterial Antibiotic Stress and Virulence
AUTHORS Hye Seon Lee, Soohyun Lee, Jun-Seob Kim, Hae-Ran Lee, Ho-Chul Shin, Moo-Seung Lee, Kyeong Sik Jin, Cheol-Hee Kim, Bonsu Ku, Choong-Min Ryu, and Seung Jun Kim ABSTRACT YfdX is ...
Read moreMultidrug resistant enteric fever in South Asia: unmet medical needs and opportunities
AUTHORS Christopher M Parry, Isabela Ribeiro, Kamini Walia, Priscilla Rupali, Stephen Baker, Buddha Basnyat ABSTRACT Enteric fever (typhoid) is the commonest bacterial bloodstream infection in South Asia. It is caused ...
Read moreEpidemiological Profile and Antimicrobial Resistance Pattern of Enteric Fever in a Tertiary Care Hospital of North India – a Seven Year Ambispective Study
AUTHORS Anuradha Makkar, Shilpi Gupta, Inam Danish Khan, Rajiv Mohan Gupta, KS Rajmohan, Harleen Chopra, Manisha Gupta, Sachin Bansal, Bindu Poonia, Muqtadir Malik, Pragyan Swagatika Panda ABSTRACT Enteric-fever is a ...
Read moreMultiple Splenic Abscesses in a Case of Enteric Fever: Salvaging Spleen through Pigtail Drainage and Antibiotics is a Good Alternative Approach
AUTHORS Vijoy Kumar Jha and Tushar Vidhale ABSTRACT Splenic abscess is a rare complication of enteric fever in developing countries. This is seen mostly solitary rather than being multiple and ...
Read moreNotes from the Field: Typhoid Fever Outbreak — Harare, Zimbabwe, October 2017–February 2018
AUTHORS Hammad S. N’cho, Kudzai P.E. Masunda, Innocent Mukeredzi, Portia Manangazira, Emmaculate Govore, Clemence Duri, Rachael D. Aubert, Haley Martin, Elizabeth Gonese, Michael Vere, Beth A. Tippett Barr, Shirish Balachandra, ...
Read moreFive-year Audit of Infectious Diseases at a Tertiary Care Hospital in Karachi, Pakistan
AUTHORS Naseem Salahuddin, Muhammad Khalid, Naila Baig-Ansari, and Sundus Iftikhar ABSTRACT Purpose To estimate the burden of infectious diseases and the seasonality of mosquito-borne diseases seen at The Indus Hospital, ...
Read moreEmergence of Extensively Drug-Resistant Salmonella Typhi Infections Among Travelers to or from Pakistan – United States, 2016-2018
AUTHORS Kevin Chatham-Stephens, Felicita Medalla, Michael Hughes, Grace D. Appiah, Rachael D. Aubert, Hayat Caidi, Kristina M. Angelo, Allison T. Walker, Noël Hatley, Sofia Masani, June Nash, John Belko, Edward ...
Read moreSalmonella enterica serovar Typhi osteomyelitis in a young adult with sickle cell and thalassemia traits: A possible association
AUTHORS Stephanie Stephanie and Sarah A. Schmalzle ABSTRACT Salmonella osteomyelitis is known to occur in immunocompromised and sickle cell disease patients. It rarely occurs in other hosts. We present a ...
Read moreHost-pathogen interactions in typhoid fever: the model is the message
AUTHORS Verónica Urdaneta and Josep Casadesús ABSTRACT Animal models are precious tools in translational research if their predictive value to human disease is high enough. In the case of typhoid ...
Read moreThe HPAfrica protocol: Assessment of health behaviour and population-based socioeconomic, hygiene behavioural factors – a standardised repeated cross-sectional study in multiple cohorts in sub-Saharan Africa
AUTHORS Gi Deok Pak, Andrea Haekyung Haselbeck, Hyeong Won Seo, Isaac Osei, John Amuasi, Robert F Breiman, Ligia Maria Cruz Espinosa, Marianne Holm, Justin Im, Geun Hyeog Jang, Hyon Jin ...
Read more21st-century typhoid fever—progression of knowledge but regression of control?
AUTHOR Karen H Keddy ABSTRACT In The Lancet Infectious Diseases, Farah Naz Qamar and colleagues detail the epidemiological investigation into an outbreak of typhoid fever in Hyderabad, Pakistan. The outbreak ...
Read moreIdentification of a Small Molecule Anti-biofilm Agent Against Salmonella enterica
AUTHOR Jasmine Moshiri, Darpan Kaur, Chido M. Hambira, Jenna L. Sandala, Jacob A. Koopman, James R. Fuchs, and John S. Gunn ABSTRACT Biofilm formation is a common strategy utilized by ...
Read moreThe phylogeography and incidence of multi-drug resistant typhoid fever in sub-Saharan Africa
AUTHOR Se Eun Park, Duy Thanh Pham, Christine Boinett, Vanessa K. Wong, Gi Deok Pak, Ursula Panzner, Ligia Maria Cruz Espinoza, Vera von Kalckreuth, Justin Im, Heidi Schütt-Gerowitt, John A. ...
Read moreVirulotyping of Salmonella enterica serovar Typhi isolates from Pakistan: Absence of complete SPI-10 in Vi negative isolates
AUTHOR Sadia Liaquat, Yasra Sarwar, Aamir Ali, Abdul Haque, Muhammad Farooq, Ilargi Martinez-Ballesteros, Lorena Laorden, Javier Garaizar, Joseba Bikandi. ABSTRACT OBJECTIVE: The distribution of virulence factors in S. Typhi can ...
Read moreSpatial and temporal heterogeneities of district-level typhoid morbidities in Ghana: A requisite insight for informed public health response
AUTHOR Frank Badu Osei, Alfred Stein, Sylvester Dodzi Nyadanu. ABSTRACT OBJECTIVE: The epidemiology of typhoid fever is poorly understood, particularly in Ghana where there has been no study of the ...
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