New data from research on the disease burden of typhoid and ways to prevent, treat, and control the disease are crucial in the fight to take on typhoid. See the latest key publications or filter and search the full list of typhoid publications below.
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Publications
Assessing the Impact of a Vi-polysaccharide Conjugate Vaccine in Preventing Typhoid Infections Among Nepalese Children: A Protocol for a Phase III, Randomized Control Trial
AUTHORS Katherine Theiss-Nyland, Mila Shakya, Rachel Colin-Jones, Merryn Voysey, Nicola Smith, Abhilasha Karkey, Sabina Dongol, Dikshya Pant, Yama G Farooq, Kathleen M Neuzil, Shrijana Shrestha, Buddha Basnyat, Andrew J Pollard BACKGROUND Enteric fever is estimated to ...
Read moreA Phase II, Randomized, Double-blind, Controlled Safety and Immunogenicity Trial of Typhoid Conjugate Vaccine in Children Under 2 Years of Age in Ouagadougou, Burkina Faso: A Methods Paper
AUTHORS Laurens MB, Sirima SB, Rotrosen ET, Siribie M, Tiono A, Ouedraogo A, Liang Y, Jamka LP, Kotloff KL, Neuzil KM ABSTRACT The recent Typhoid Fever Surveillance in Africa Program ...
Read moreAntibiotic Resistance and Typhoid
AUTHORS Dyson ZA, Klemm EJ, Palmer S, Dougan G ABSTRACT Multiple drug (antibiotic) resistance (MDR) has become a major threat to the treatment of typhoid and other infectious diseases. Since ...
Read moreIncidence of Typhoid and Paratyphoid Fevers Among Adolescents and Adults in Yangon, Myanmar
AUTHORS Oo WT, Myat TO, Htike WW, Ussher JE, Murdoch DR, Lwin KT, Oo MZ, Maze MJ, Win HH, Crump JA BACKGROUND Accurate estimates of typhoid disease burden are needed ...
Read moreAssessing the Impact of a Vi-polysaccharide Conjugate Vaccine in Preventing Typhoid Infection Among Bangladeshi Children: A Protocol for a Phase IIIb Trial
AUTHORS Theiss-Nyland K, Qadri F, Colin-Jones R, Zaman K, Khanam F, Liu X, Voysey M, Khan A, Hasan N, Ashher F, Farooq YG, Pollard AJ, Clemens JD BACKGROUND Typhoid fever ...
Read moreA Review of the Economic Evidence of Typhoid Fever and Typhoid Vaccines
AUTHORS Luthra K, Watts E, Debellut F, Pecenka C, Bar-Zeev N, Constenla D ABSTRACT Typhoid places a substantial economic burden on low- and middle-income countries. We performed a literature review ...
Read moreLogistics of Implementing a Large-scale Typhoid Vaccine Trial in Kathmandu, Nepal
AUTHORS Colin-Jones R, Shakya M, Voysey M, Theiss-Nyland K, Smith N, Pant D, Liu X, Tonks S, Mazur O, Farooq YG, Kelly S, Adhikari A, Dongol S, Karkey A, Shrestha ...
Read moreGlobal Typhoid Fever Incidence: A Systematic Review and Meta-analysis
AUTHORS Christian S Marchello, Chuen Yen Hong, and John A Crump BACKGROUND Contemporary incidence estimates of typhoid fever are needed to guide policy decisions and control measures and to improve ...
Read moreSalmonella Typhi From Blood Cultures in the Democratic Republic of the Congo: A 10-Year Surveillance
AUTHORS Tack B, Phoba MF, Van Puyvelde S Kalonji LM, Hardy L, Barbé B, Van der Sande MAB, Monsieurs E, Deborggraeve S, Lunguya O, Jacobs J BACKGROUND This study gives ...
Read moreAnalysis of Salmonella enterica Serovar Typhi by Outer Membrane Protein (OMP) Profiling, Random Amplification of Polymorphic DNA (RAPD) and Pulsed Field Gel Electrophoresis (PFGE)
AUTHORS Yashwant Kumar, Kavaratty Raju Mani, and Ajay Kumar Tahlan ABSTRACT A number of countries, including developed countries, still have typhoid fever as a major problem resulting in frequent outbreaks. ...
Read moreMolecular analysis of clonally related Salmonella Typhi recovered from epidemiologically unrelated cases of typhoid fever, Brazil
AUTHORS Tiba-Casas MR, Sacchi CT, Gonçalves CR, Almeida EA, Soares FB, de Jesus Bertani AM, Fernandes SA, de Paula Eduardo MB, Camargo CH. BACKGROUND The primary method of molecular subtyping ...
Read moreSix-month follow up of a randomized clinical trial-phase I study in Indonesian adults and children: Safety and immunogenicity of Salmonella typhi polysaccharide-diphtheria toxoid (Vi-DT) conjugate vaccine
AUTHORS Medise BE, Soedjatmiko S, Rengganis I, Gunardi H, Sekartini R, Koesno S, Satari HI, Hadinegoro SR, Yang JS, Excler JL, Sahastrabuddhe S, Puspita M, Sari RM, Bachtiar NS. INTRODUCTION There is a high global incidence of typhoid fever, with an annual mortality ...
Read moreLoop-mediated isothermal amplification (LAMP) for paratyphoid fever – a proof-of-principle analysis
AUTHORS Rojak S, Wiemer DF, Wille A, Loderstädt U, Wassill L, Hinz R, Hagen RM, Frickmann H. ABSTRACT In‐house loop‐mediated isothermal amplification (LAMP) procedures for the detection of paratyphoid fever associated bacteria on serovar level were evaluated. ...
Read moreIdentification of Genes Involved in Biogenesis of Outer Membrane Vesicles (OMVs) in Salmonella enterica Serovar Typhi
AUTHORS Jan Nevermann, Andrés Silva, Carolina Otero, Diego P. Oyarzún, Boris Barrera, Fernando Gil, Iván L. Calderón, and Juan A. Fuentes ABSTRACT Outer membrane vesicles (OMVs) are nano-sized proteoliposomes discharged ...
Read moreThe global burden of typhoid and paratyphoid fevers: a systematic analysis for the Global Burden of Disease Study 2017
AUTHORS GBD 2017 Typhoid and Paratyphoid Collaborators. BACKGROUND Efforts to quantify the global burden of enteric fever are valuable for understanding the health lost and the large-scale spatial distribution of ...
Read moreEvidence to Action: The 10th International Conference on Typhoid and Other Invasive Salmonelloses
AUTHORS Sarah Lindsay, Denise Garrett, and Duncan Steele ABSTRACT Typhoid and other invasive salmonelloses continue to cause a significant burden of disease, including morbidity, mortality, and financial cost, in low- ...
Read moreA Global Agenda for Typhoid Control-A Perspective from the Bill & Melinda Gates Foundation
AUTHORS Carey ME, Diaz ZI, Zaidi AKM, Steele AD. ABSTRACT Recognizing that enteric fever disproportionately affects the poorest and the most vulnerable communities that have limited access to improved sanitation, ...
Read moreProgress in Typhoid Fever Epidemiology
AUTHORS John A Crump ABSTRACT Salmonella enterica subspecies enterica serovar Typhi (Salmonella Typhi) is the cause of typhoid fever and a human host–restricted organism. Our understanding of the global burden ...
Read moreRevised Global Typhoid Vaccination Policy
AUTHORS Adwoa D Bentsi-Enchill and Joachim Hombach ABSTRACT Typhoid fever is a continuing public health problem in many low- and middle-income countries; however, routine vaccination as a recommended control strategy ...
Read moreOverview of the Typhoid Conjugate Vaccine Pipeline: Current Status and Future Plans
AUTHORS Sushant Sahastrabuddhe and Tarun Saluja ABSTRACT Typhoid fever remains a common and serious disease in populations that live in low- and middle-income countries. Treatment usually consists of antibiotics, but ...
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