New data from research on the disease burden of typhoid and ways to prevent, treat, and control the disease are crucial in the fight to take on typhoid. See the latest key publications or filter and search the full list of typhoid publications below.
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Relapse of typhoid fever following delayed response to meropenem: A case report and review of previously published cases indicating limited clinical efficacy of meropenem for the treatment of typhoid fever
AUTHORS Blumentrath CG, Müller G, Teichmann D, Tiesmeier J, Petridou J ABSTRACT In times of emerging multi-drug resistance among Gram-negative bacteria (including Salmonella enterica, Serovar Typhi), we observed relapse of ...
Read moreThe Coalition Against Typhoid: Mobilizing a Community for a Global Fight
AUTHORS Lindsay S, Gellin B, Lee A, Garrett D ABSTRACT Typhoid became a low priority on the global public health agenda when it was largely eliminated from developed countries in ...
Read moreTyphoid Vaccine Acceleration Consortium Malawi: A Phase III, Randomized, Double-blind, Controlled Trial of the Clinical Efficacy of Typhoid Conjugate Vaccine Among Children in Blantyre, Malawi
AUTHORS Meiring JE, Laurens MB, Patel P, Patel P, Misiri T, Simiyu K, Mwakiseghile F, Tracy JK, Masesa C2, Liang Y, Henrion M, Rotrosen E, Gmeiner M, Heyderman R, Kotloff ...
Read moreForecasting Demand for the Typhoid Conjugate Vaccine in Low- and Middle-income Countries
AUTHORS Debellut F, Hendrix N, Pitzer VE, Neuzil KM, Constenla D, Bar-Zeev N, Marfin A, Pecenka C BACKGROUND The World Health Organization (WHO) released a position paper in March 2018 ...
Read moreCommunity Engagement Before Initiation of Typhoid Conjugate Vaccine Trial in Schools in Two Urban Townships in Blantyre, Malawi: Experience and Lessons
AUTHORS Meiring JE, Sambakunsi R, Moyo E, Misiri T, Mwakiseghile F, Patel P, Patel P, Ndaferankhande J, Laurens M, Gooding K, Gordon MA BACKGROUND To determine the efficacy of a ...
Read morePredicting the Impact of Typhoid Conjugate Vaccines on Antimicrobial Resistance
AUTHORS Samantha Kaufhold, Reza Yaesoubi, and Virginia E Pitzer BACKGROUND Empiric prescribing of antimicrobials in typhoid-endemic settings has increased selective pressure on the development of antimicrobial-resistant Salmonella enterica serovar Typhi. ...
Read moreEpidemiology of Typhoid and Paratyphoid: Implications for Vaccine Policy
AUTHORS Saha S, Islam MS, Sajib MSI, Saha S, Uddin MJ, Hooda Y, Hasan M, Amin MR, Hanif M, Shahidullah M, Islam M, Luby SP, Andrews JR, Saha SK BACKGROUND ...
Read moreThe Design and Analysis of Seroefficacy Studies for Typhoid Conjugate Vaccines
AUTHORS Liu X, Pitzer VE, Pollard AJ, Voysey M BACKGROUND Demonstrating the efficacy of new Vi-conjugate typhoid vaccines is challenging, due to the cost of field trials requiring tens of ...
Read moreThe Time is Now to Control Typhoid
AUTHORS Andrew J Pollard, Anthony A Marfin, and Kathleen M Neuzil ABSTRACT The death of Prince Albert, married to Queen Victoria of the United Kingdom, in 1861 from typhoid profoundly ...
Read moreAccelerating Typhoid Conjugate Vaccine Introduction: What Can Be Learned From Prior New Vaccine Introduction Initiatives?
AUTHORS Jamka LP, Simiyu KW, Bentsi-Enchill AD, Mwisongo AJ, Matzger H, Marfin AA, Pollard AJ, Neuzil KM ABSTRACT The health consequences of typhoid, including increasing prevalence of drug-resistant strains, can ...
Read moreAssessing the Impact of a Vi-polysaccharide Conjugate Vaccine in Preventing Typhoid Infections Among Nepalese Children: A Protocol for a Phase III, Randomized Control Trial
AUTHORS Katherine Theiss-Nyland, Mila Shakya, Rachel Colin-Jones, Merryn Voysey, Nicola Smith, Abhilasha Karkey, Sabina Dongol, Dikshya Pant, Yama G Farooq, Kathleen M Neuzil, Shrijana Shrestha, Buddha Basnyat, Andrew J Pollard BACKGROUND Enteric fever is estimated to ...
Read moreA Phase II, Randomized, Double-blind, Controlled Safety and Immunogenicity Trial of Typhoid Conjugate Vaccine in Children Under 2 Years of Age in Ouagadougou, Burkina Faso: A Methods Paper
AUTHORS Laurens MB, Sirima SB, Rotrosen ET, Siribie M, Tiono A, Ouedraogo A, Liang Y, Jamka LP, Kotloff KL, Neuzil KM ABSTRACT The recent Typhoid Fever Surveillance in Africa Program ...
Read moreAntibiotic Resistance and Typhoid
AUTHORS Dyson ZA, Klemm EJ, Palmer S, Dougan G ABSTRACT Multiple drug (antibiotic) resistance (MDR) has become a major threat to the treatment of typhoid and other infectious diseases. Since ...
Read moreIncidence of Typhoid and Paratyphoid Fevers Among Adolescents and Adults in Yangon, Myanmar
AUTHORS Oo WT, Myat TO, Htike WW, Ussher JE, Murdoch DR, Lwin KT, Oo MZ, Maze MJ, Win HH, Crump JA BACKGROUND Accurate estimates of typhoid disease burden are needed ...
Read moreAssessing the Impact of a Vi-polysaccharide Conjugate Vaccine in Preventing Typhoid Infection Among Bangladeshi Children: A Protocol for a Phase IIIb Trial
AUTHORS Theiss-Nyland K, Qadri F, Colin-Jones R, Zaman K, Khanam F, Liu X, Voysey M, Khan A, Hasan N, Ashher F, Farooq YG, Pollard AJ, Clemens JD BACKGROUND Typhoid fever ...
Read moreA Review of the Economic Evidence of Typhoid Fever and Typhoid Vaccines
AUTHORS Luthra K, Watts E, Debellut F, Pecenka C, Bar-Zeev N, Constenla D ABSTRACT Typhoid places a substantial economic burden on low- and middle-income countries. We performed a literature review ...
Read moreLogistics of Implementing a Large-scale Typhoid Vaccine Trial in Kathmandu, Nepal
AUTHORS Colin-Jones R, Shakya M, Voysey M, Theiss-Nyland K, Smith N, Pant D, Liu X, Tonks S, Mazur O, Farooq YG, Kelly S, Adhikari A, Dongol S, Karkey A, Shrestha ...
Read moreGlobal Typhoid Fever Incidence: A Systematic Review and Meta-analysis
AUTHORS Christian S Marchello, Chuen Yen Hong, and John A Crump BACKGROUND Contemporary incidence estimates of typhoid fever are needed to guide policy decisions and control measures and to improve ...
Read moreSalmonella Typhi From Blood Cultures in the Democratic Republic of the Congo: A 10-Year Surveillance
AUTHORS Tack B, Phoba MF, Van Puyvelde S Kalonji LM, Hardy L, Barbé B, Van der Sande MAB, Monsieurs E, Deborggraeve S, Lunguya O, Jacobs J BACKGROUND This study gives ...
Read moreAnalysis of Salmonella enterica Serovar Typhi by Outer Membrane Protein (OMP) Profiling, Random Amplification of Polymorphic DNA (RAPD) and Pulsed Field Gel Electrophoresis (PFGE)
AUTHORS Yashwant Kumar, Kavaratty Raju Mani, and Ajay Kumar Tahlan ABSTRACT A number of countries, including developed countries, still have typhoid fever as a major problem resulting in frequent outbreaks. ...
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