New data from research on the disease burden of typhoid and ways to prevent, treat, and control the disease are crucial in the fight to take on typhoid. See the latest key publications or filter and search the full list of typhoid publications below.
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Publications
Age-Associated Heterogeneity of Ty21a-Induced T Cell Responses to HLA-E Restricted Salmonella Typhi Antigen Presentation
AUTHORS Mark E. Rudolph, Monica A. McArthur, Laurence S. Magder, Robin S. Barnes, Wilbur H. Chen, and Marcelo B. Sztein ABSTRACT Human-restricted Salmonella enterica serovar Typhi (S. Typhi) is the causative ...
Read moreSalmonella enterica serovar enteritidis peritonitis with spontaneous intestinal perforation in an immunocompetent patient
AUTHORS Hélias M, Planchon J, Bousquet A, Dubost C ABSTRACT Few data reported non-typhoidal Salmonella peritonitis in immunocompromised patients. We reported the case of a man without immunosuppression or predisposing ...
Read moreCharacteristics of regulatory T-cell populations before and after Ty21a typhoid vaccination in children and adults
AUTHORS Mark E. Rudolph, Monica A. McArthur, Laurence S. Magder, Robin S. Barnes, Wilbur H. Chen, Marcelo B. Sztein ABSTRACT Typhoid fever, caused by the pathogen Salmonella enterica serovar Typhi ...
Read moreExtensively drug-resistant typhoid fever in Pakistan
AUTHORS Muhammad Kamran Rasheed, Syed Shahzad Hasan, Zaheer-Ud-Din Babar, Syed Imran Ahmed ABSTRACT We read the Article by Farah Qamar and colleagues about the outbreak of ceftriaxone-resistant Salmonella enterica serotype ...
Read moreAssociation between S. Typhi-specific memory CD4+ and CD8+ T responses in the terminal ileum mucosa and in peripheral blood elicited by the live oral typhoid vaccine Ty21a in humans
AUTHORS Booth JS, Goldberg E, Patil SA, Greenwald BD, Sztein MB ABSTRACT CD4+ and CD8+ T subsets are essential components of the adaptive immune system which act in concert at ...
Read moreRelapse of typhoid fever following delayed response to meropenem: A case report and review of previously published cases indicating limited clinical efficacy of meropenem for the treatment of typhoid fever
AUTHORS Blumentrath CG, Müller G, Teichmann D, Tiesmeier J, Petridou J ABSTRACT In times of emerging multi-drug resistance among Gram-negative bacteria (including Salmonella enterica, Serovar Typhi), we observed relapse of ...
Read moreThe Coalition Against Typhoid: Mobilizing a Community for a Global Fight
AUTHORS Lindsay S, Gellin B, Lee A, Garrett D ABSTRACT Typhoid became a low priority on the global public health agenda when it was largely eliminated from developed countries in ...
Read moreTyphoid Vaccine Acceleration Consortium Malawi: A Phase III, Randomized, Double-blind, Controlled Trial of the Clinical Efficacy of Typhoid Conjugate Vaccine Among Children in Blantyre, Malawi
AUTHORS Meiring JE, Laurens MB, Patel P, Patel P, Misiri T, Simiyu K, Mwakiseghile F, Tracy JK, Masesa C2, Liang Y, Henrion M, Rotrosen E, Gmeiner M, Heyderman R, Kotloff ...
Read moreForecasting Demand for the Typhoid Conjugate Vaccine in Low- and Middle-income Countries
AUTHORS Debellut F, Hendrix N, Pitzer VE, Neuzil KM, Constenla D, Bar-Zeev N, Marfin A, Pecenka C BACKGROUND The World Health Organization (WHO) released a position paper in March 2018 ...
Read moreCommunity Engagement Before Initiation of Typhoid Conjugate Vaccine Trial in Schools in Two Urban Townships in Blantyre, Malawi: Experience and Lessons
AUTHORS Meiring JE, Sambakunsi R, Moyo E, Misiri T, Mwakiseghile F, Patel P, Patel P, Ndaferankhande J, Laurens M, Gooding K, Gordon MA BACKGROUND To determine the efficacy of a ...
Read morePredicting the Impact of Typhoid Conjugate Vaccines on Antimicrobial Resistance
AUTHORS Samantha Kaufhold, Reza Yaesoubi, and Virginia E Pitzer BACKGROUND Empiric prescribing of antimicrobials in typhoid-endemic settings has increased selective pressure on the development of antimicrobial-resistant Salmonella enterica serovar Typhi. ...
Read moreEpidemiology of Typhoid and Paratyphoid: Implications for Vaccine Policy
AUTHORS Saha S, Islam MS, Sajib MSI, Saha S, Uddin MJ, Hooda Y, Hasan M, Amin MR, Hanif M, Shahidullah M, Islam M, Luby SP, Andrews JR, Saha SK BACKGROUND ...
Read moreThe Design and Analysis of Seroefficacy Studies for Typhoid Conjugate Vaccines
AUTHORS Liu X, Pitzer VE, Pollard AJ, Voysey M BACKGROUND Demonstrating the efficacy of new Vi-conjugate typhoid vaccines is challenging, due to the cost of field trials requiring tens of ...
Read moreThe Time is Now to Control Typhoid
AUTHORS Andrew J Pollard, Anthony A Marfin, and Kathleen M Neuzil ABSTRACT The death of Prince Albert, married to Queen Victoria of the United Kingdom, in 1861 from typhoid profoundly ...
Read moreAccelerating Typhoid Conjugate Vaccine Introduction: What Can Be Learned From Prior New Vaccine Introduction Initiatives?
AUTHORS Jamka LP, Simiyu KW, Bentsi-Enchill AD, Mwisongo AJ, Matzger H, Marfin AA, Pollard AJ, Neuzil KM ABSTRACT The health consequences of typhoid, including increasing prevalence of drug-resistant strains, can ...
Read moreAssessing the Impact of a Vi-polysaccharide Conjugate Vaccine in Preventing Typhoid Infections Among Nepalese Children: A Protocol for a Phase III, Randomized Control Trial
AUTHORS Katherine Theiss-Nyland, Mila Shakya, Rachel Colin-Jones, Merryn Voysey, Nicola Smith, Abhilasha Karkey, Sabina Dongol, Dikshya Pant, Yama G Farooq, Kathleen M Neuzil, Shrijana Shrestha, Buddha Basnyat, Andrew J Pollard BACKGROUND Enteric fever is estimated to ...
Read moreA Phase II, Randomized, Double-blind, Controlled Safety and Immunogenicity Trial of Typhoid Conjugate Vaccine in Children Under 2 Years of Age in Ouagadougou, Burkina Faso: A Methods Paper
AUTHORS Laurens MB, Sirima SB, Rotrosen ET, Siribie M, Tiono A, Ouedraogo A, Liang Y, Jamka LP, Kotloff KL, Neuzil KM ABSTRACT The recent Typhoid Fever Surveillance in Africa Program ...
Read moreAntibiotic Resistance and Typhoid
AUTHORS Dyson ZA, Klemm EJ, Palmer S, Dougan G ABSTRACT Multiple drug (antibiotic) resistance (MDR) has become a major threat to the treatment of typhoid and other infectious diseases. Since ...
Read moreIncidence of Typhoid and Paratyphoid Fevers Among Adolescents and Adults in Yangon, Myanmar
AUTHORS Oo WT, Myat TO, Htike WW, Ussher JE, Murdoch DR, Lwin KT, Oo MZ, Maze MJ, Win HH, Crump JA BACKGROUND Accurate estimates of typhoid disease burden are needed ...
Read moreAssessing the Impact of a Vi-polysaccharide Conjugate Vaccine in Preventing Typhoid Infection Among Bangladeshi Children: A Protocol for a Phase IIIb Trial
AUTHORS Theiss-Nyland K, Qadri F, Colin-Jones R, Zaman K, Khanam F, Liu X, Voysey M, Khan A, Hasan N, Ashher F, Farooq YG, Pollard AJ, Clemens JD BACKGROUND Typhoid fever ...
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