New data from research on the disease burden of typhoid and ways to prevent, treat, and control the disease are crucial in the fight to take on typhoid. See the latest key publications or filter and search the full list of typhoid publications below.
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Invasive non-typhoidal Salmonella in sickle cell disease in Africa: is increased gut permeability the missing link?
AUTHORS Seah H. Lim, Barbara A. Methé, Bettina M. Knoll, Alison Morris, Stephen K. Obaro ABSTRACT Non-typhoidal Salmonella usually induces self-limiting gastroenteritis. However, in many parts of Africa, especially in ...
Read moreRubicon-Dependent Lc3 Recruitment to Salmonella-Containing Phagosomes Is a Host Defense Mechanism Triggered Independently From Major Bacterial Virulence Factors
AUTHORS Samrah Masud, Lars van der Burg, Lisanne Storm, Tomasz K. Prajsnar, Annemarie H. Meijer ABSTRACT Intracellular pathogens such as Salmonella depend on their molecular virulence factors to evade host ...
Read moreExpansion of Salmonella Typhi clonal lineages with ampicillin resistance and reduced ciprofloxacin susceptibility in Eastern China
AUTHORS Dingfeng Lv, Danyang Zhang, Qifa Song ABSTRACT This study was aimed to investigate the dynamics of antimicrobial resistance expansion among different lineages and isolates of S. Typhi. The S. ...
Read moreEpidemiological Trend of Typhoid and Paratyphoid Fevers in Zhejiang Province, China from 1953 to 2014
AUTHORS Hua Gu, Congcong Yan, Zhenggang Jiang, Xiuyang Li, Enfu Chen, Jianmin Jiang, Qingwu Jiang, Yibiao Zhou ABSTRACT The incidences of typhoid and paratyphoid remain high and these diseases still pose a public health ...
Read moreCombined vaccines for prophylaxis of infectious conditions
AUTHORS Pravin Shende, Mansi Waghchaure ABSTRACT In recent years, the application of vaccines shows limitations, including the high number of vaccine administrations and the fear of safety and effectiveness. In ...
Read moreModelling the cost-effectiveness of a rapid diagnostic test (IgMFA) for uncomplicated typhoid fever in Cambodia
AUTHORS Mari Kajiwara Saito, Christopher M. Parry, Shunmay Yeung ABSTRACT Typhoid fever is a common cause of fever in Cambodian children but diagnosis and treatment are usually presumptive owing to ...
Read moreEffect of in-line drinking water chlorination at the point of collection on child diarrhoea in urban Bangladesh: a double-blind, cluster-randomised controlled trial
AUTHORS Amy J Pickering, Yoshika Crider, Sonia Sultana, Jenna Swarthout, Frederick GB Goddard, Syed Anjerul Islam, Shreyan Sen, Raga Ayyagari, Stephen P Luby ABSTRACT Previous blinded trials of household water treatment interventions in ...
Read moreSalmonella neck abscess in a diabetic
AUTHORS Nathan McLeod, Allison Lastinger, Nicole Bryan, Theodore Kieffer, Trevor Wolfe ABSTRACT Salmonella is known to cause invasive illness. However, head and neck abscesses are an unusual presentation of extra-intestinal infection ...
Read moreTyphoidal Salmonella strains in Pakistan: an impending threat of extensively drug-resistant Salmonella Typhi
AUTHORS Ashfaq Hussain, Luqman Satti, Faisal Hanif, Nadia Midhat Zehra, Saman Nadeem, Tariq Mehmood Bangash, and Aqeel Peter ABSTRACT The aim of this study is to see the frequency, clinical presentation, ...
Read moreEarly Economic Evaluation to Identify the Necessary Test Characteristics of a New Typhoid Test to be Cost Effective in Ghana
AUTHORS Samuel N. Frempong, Andrew J. Sutton, Clare Davenport, and Pelham Barton ABSTRACT In Ghana, there are issues with the diagnosis of typhoid fever; these include delays in diagnosis, concerns about ...
Read moreSuccessful endoscopic hemoclipping and conservative management for typhoid fever complicated by massive intestinal bleeding and acute pancreatitis: Case report
AUTHORS Joon Cho ABSTRACT Massive intestinal bleeding as a complication of typhoid fever has rarely been reported due to the advent of antibiotics. In addition, although several literatures have been issued on ...
Read moreAn Unusual Case of Extensively Drug Resistant Typhoid Fever
AUTHORS Jamil M. Bhatti, Yousuf Memon, Samreen Sarfaraz, Naseem Salahuddin ABSTRACT Enteric fever is a potentially fatal multisystemic illness caused primarily by Salmonella typhi and, to a lesser extent, by Paratyphi A, B, and C. ...
Read moreThe ADP-Ribosylating Toxins of Salmonella
AUTHORS Rachel A. Cheng and Martin Wiedmann ABSTRACT A number of pathogenic bacteria utilize toxins to mediate disease in a susceptible host. The foodborne pathogen Salmonella is one of the most important and ...
Read moreAscertaining the burden of invasive Salmonella disease in hospitalised febrile children aged under four years in Blantyre, Malawi
AUTHORS Chisomo L. Msefula, Franziska Olgemoeller, Ndaru Jambo, Dalitso Segula, Trinh Van Tan, Tonney S. Nyirenda, Wilfred Nedi, Neil Kennedy, Matthew Graham, Marc Y. R. Henrion, Stephen Baker, Nicholas Feasey, ...
Read moreClinical Evaluation of a Multiplex PCR for the Detection of Salmonella enterica Serovars Typhi and Paratyphi A from Blood Specimens in a High-Endemic Setting.
AUTHORS Stephane Pouzol, Arif Mohammad Tanmoy, Dilruba Ahmed, Farhana Khanam, W. Abdullah Brooks,Golam Sarower Bhuyan, Laetitia Fabre, Juliet E. Bryant, Marie-Paule Gustin, Philippe Vanhems, Bill Carman, François-Xavier Weill, Firdausi Qadri, Samir Saha and Hubert Endtz ABSTRACT Enteric fever is a major public health concern ...
Read moreEnvironmental Foundations of Typhoid Fever in the Fijian Residential Setting.
AUTHORS Aaron P. Jenkins, Stacy D. Jupiter, Adam Jenney, Varanisese Rosa, Alanieta Naucukidi, Namrata Prasad, Gandercillar Vosaki, Kim Mulholland, Richard Strugnell, Mike Kama, John A. Crump and Pierre Horwitz ABSTRACT ...
Read moreDiversity of infectious aetiologies of acute undifferentiated febrile illnesses in south and Southeast Asia: a systematic review
AUTHORS Kinley Wangdi, Kaushalya Kasturiaratchi, Susana Vaz Nery, Colleen L. Lau, Darren J. Gray and Archie C. A. Clements ABSTRACT Acute undifferentiated febrile illness (AUFI) is caused by a multitude of diverse pathogens, with significant morbidity and mortality ...
Read moreInvestigation of the role of typhoid toxin in acute typhoid fever in a human challenge model
AUTHORS Malick M. Gibani, Elizabeth Jones, Amber Barton, Celina Jin, Juliette Meek, Susana Camara, Ushma Galal, Eva Heinz, Yael Rosenberg-Hasson, Gerlinde Obermoser, Claire Jones, Danielle Campbell, Charlotte Black, Helena Thomaides-Brears, Christopher Darlow, Christina Dold, Laura Silva-Reyes, Luke Blackwell, Maria Lara-Tejero, Xuyao Jiao, Gabrielle Stack, Christoph J. Blohmke, Jennifer Hill, Brian Angus, Gordon Dougan, Jorge ...
Read moreRestraining the multidrug efflux transporter STY4874 of Salmonella Typhi by reserpine and plant extracts.
AUTHORS Anam Tariq, Maryam Sana, Aqsa Shaheen, Fouzia Ismat, Sadia Mahboob, Waqar Rauf, Osman Mirza, Mazhar Iqbal, and Moazur Rahman ABSTRACT Efflux mediated multidrug resistance is a well-known phenomenon facilitated ...
Read moreCase Report: Typhoid Fever Complicated by Acute Respiratory Distress Syndrome in a Pediatric Traveler: A Case Report and Review of the Literature
AUTHORS Morgan Birabaharan, Mundeep K. Kainth, Aaron D. Kessel and Stefan H. F. Hagmann ABSTRACT Acute respiratory distress syndrome (ARDS) is seldom described as a complication of typhoid fever (TF). Only 13 cases have hitherto been ...
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