New data from research on the disease burden of typhoid and ways to prevent, treat, and control the disease are crucial in the fight to take on typhoid. See the latest key publications or filter and search the full list of typhoid publications below.
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Molecular mechanism of azithromycin resistance among typhoidal Salmonella strains in Bangladesh identified through passive pediatric surveillance.
AUTHORS Hooda Y, Sajib MSI, Rahman H, Luby SP, Bondy-Denomy J, Santosham M, Andrews JR, Saha SK, Saha S ABSTRACT Background: With the rise in fluoroquinolone-resistant Salmonella Typhi and the ...
Read moreTravel-Related Typhoid Fever: Narrative Review of the Scientific Literature
AUTHORS Muresu N, Sotgiu G, Are BM, Cossu A, Cocuzza C, Martinelli M, Babudieri S, Are R, Dettori M, Azara A, Saderi L, Piana A ABSTRACT Enteric fever is a ...
Read moreEpidemiology profil of fever typhoid in Meknes (Morocco) 2013–2016
AUTHORS M. Essayagh, A. El Rhaffouli, S. Essayagh, T. Essayagh ABSTRACT Introduction: Twenty million cases of typhoid and paratyphoid fever (TF) are observed annually worldwide with more than 200,000 deaths. These ...
Read moreUnder-detection of blood culture-positive enteric fever cases: The impact of missing data and methods for adjusting incidence estimates
AUTHORS Merryn Voysey, Dikshya Pant, Mila Shakya, Xinxue Liu, Rachel Colin-Jones, Katherine Theiss-Nyland, Nicola Smith, Shrijana Shrestha, Buddha Basnyat, Andrew J Pollard, Virginia E Pitzer ABSTRACT Background: In surveillance for ...
Read moreMechanisms of Substrate Recognition by a Typhoid Toxin Secretion-Associated Muramidase
AUTHORS Tobias Geiger, Maria Lara-Tejero, Yong Xiong, Jorge E Galán ABSTRACT Typhoid toxin is a virulence factor for the bacterial pathogen Salmonella Typhi, which causes typhoid fever in humans. After ...
Read moreThe YrbE phospholipid transporter of Salmonella enterica serovar Typhi regulates the expression of flagellin and influences motility, adhesion and induction of epithelial inflammatory responses
AUTHORS Smriti Verma, Rachel A Prescott, Laura Ingano, Kourtney P Nickerson, Emily Hill, Christina S Faherty, Alessio Fasano, Stefania Senger, Bobby J Cherayil ABSTRACT Salmonella enterica serovar Typhi is the ...
Read moreCost-effectiveness of using environmental surveillance to target the roll-out typhoid conjugate vaccine
AUTHORS Brittany L Hagedorn, Jillian Gauld, Nicholas Feasey, Hao Hu ABSTRACT Highlights •Environmental surveillance is an alternative to case-based surveillance •Vaccine targeted to high-risk populations is less expensive than national ...
Read moreCrosstalk between leukocytes triggers differential immune responses against Salmonella enterica serovars Typhi and Paratyphi
AUTHORS Rosangela Salerno-Goncalves, Darpan Kayastha, Alessio Fasano, Myron M. Levine, Marcelo B. Sztein ABSTRACT Enteric fevers, caused by the Salmonella enterica serovars Typhi (ST), Paratyphi A (PA) and Paratyphi B ...
Read morePlasmid profiling and incompatibility grouping of multidrug resistant Salmonella enterica serovar Typhi isolates in Nairobi, Kenya
AUTHORS Winnie C. Mutai, Peter G. Waiyaki, Samuel Kariuki, Anne W. T. Muigai ABSTRACT Objectives: Plasmids harbour antibiotic resistance genes which contribute to the emergence of multidrug resistant pathogens. We ...
Read moreA phase 1 randomized safety, reactogenicity, and immunogenicity study of Typhax: A novel protein capsular matrix vaccine candidate for the prevention of typhoid fever
AUTHORS Robert T. Cartee, Ann Thanawastien, Thomas J. Griffin IV, John J. Mekalanos, Stephan Bart, Kevin P. Killeen ABSTRACT Background: Typhoid fever remains a significant cause of morbidity and mortality ...
Read moreLAMF9 is found on select subsets of antigen-presenting cells and promotes resistance to Salmonella infection
AUTHORS Wilson TJ, Clare S, Mikulin J, Johnson CM, Harcourt K, Lyons PA, Dougan G, Smith KGC ABSTRACT SLAMF9 is an orphan receptor of the CD2/SLAM family of leucocyte surface ...
Read moreOccurrence of Salmonella infection and antimicrobial susceptibility for local Salmonella isolates from different sources in a cross-sectional study
AUTHORS Abdelmalek S, Kadry M, Elshafiee EA, Hamed W, Moussa IM, Al-Maary KS, Mubarak AS, Hemeg HA, Elbehiry A ABSTRACT Salmonellosis is a considerable public health problem worldwide, with high ...
Read moreCharacterization of non-typhoidal Salmonella isolates from children with acute gastroenteritis, Kolkata, India, during 2000–2016
AUTHORS Jain P, Chowdhury G, Samajpati S, Basak S, Ganai A, Samanta S, Okamoto K, Mukhopadhyay AK, Dutta S ABSTRACT Non-typhoidal Salmonella (NTS) is an important cause of acute gastroenteritis ...
Read moreDrug-resistant enteric fever worldwide, 1990 to 2018: a systematic review and meta-analysis
AUTHORS Browne AJ, Kashef Hamadani BH, Kumaran EAP, Rao P, Longbottom J, Harriss E, Moore CE, Dunachie S, Basnyat B, Baker S, Lopez AD, Day NPJ, Hay SI, Dolecek C ...
Read moreBacterial pathogens and resistance causing community acquired paediatric bloodstream infections in low- and middle-income countries: a systematic review and meta-analysis
AUTHORS Droz N, Hsia Y, Ellis S, Dramowski A, Sharland M, Basmaci R ABSTRACT Background: Despite a high mortality rate in childhood, there is limited evidence on the causes and ...
Read moreDistinct climate influences on the risk of typhoid compared to invasive non-typhoid Salmonella disease in Blantyre, Malawi
AUTHORS Deus Thindwa, Michael G. Chipeta, Marc Y. R. Henrion, Melita A. Gordon ABSTRACT Invasive Salmonella diseases, both typhoid and invasive non-typhoidal Salmonella (iNTS), are seasonal bloodstream infections causing important ...
Read moreWhy do participants drop-out: findings from a prospective pediatric cohort for fever surveillance established at Vellore, southern India
AUTHORS Sindhu KN, Srinivasan M, Subramaniam S, David AS, Mohan VR, John J, Kang G ABSTRACT Background: Cohort studies are pivotal in understanding the natural history, and to thereby determine ...
Read moreSalmonella typhi Meningitis in an Immunocompetent Asian Adult
AUTHORS Rashid Nadeem , Naheed Elahi, Ashraf Elhoufi, Ahmed Elsousi, Monazza Chaudhry ABSTRACT Enteric salmonella infections are common in the United States though nonenteric salmonella infections in immunocompetent adults are ...
Read moreInvestigating host-bacterial interactions among enteric pathogens
AUTHORS Tungadri Bose, K. V. Venkatesh, Sharmila S. Mande ABSTRACT Background: In 2017, World Health Organization (WHO) published a catalogue of 12 families of antibiotic-resistant “priority pathogens” that are posing ...
Read moreTreatment responses to Azithromycin and Ciprofloxacin in uncomplicated Salmonella Typhi infection: A comparison of Clinical and Microbiological Data from a Controlled Human Infection Model
AUTHORS Jin C, Gibani MM, Pennington SH, Liu X, Ardrey A, Aljayyoussi G, Moore M, Angus B, Parry CM, Biagini GA, Feasey NA, Pollard AJ ABSTRACT Background: The treatment of ...
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