New data from research on the disease burden of typhoid and ways to prevent, treat, and control the disease are crucial in the fight to take on typhoid. See the latest key publications or filter and search the full list of typhoid publications below.
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Update on Extensively Drug-Resistant Salmonella Serotype Typhi Infections Among Travelers to or From Pakistan and Report of Ceftriaxone-Resistant Salmonella Serotype Typhi Infections Among Travelers to Iraq – United States, 2018-2019
AUTHORS Louise K François Watkins, Alison Winstead, Grace D Appiah, Cindy R Friedman, Felicita Medalla, Michael J Hughes, Meseret G Birhane, Zachary D Schneider, Perrine Marcenac, Samir S Hanna, Gauri Godbole, Kelly A Walblay, Ashley E Wiggington, Molly Leeper, Elizabeth H Meservey, Kaitlin A Tagg, Jessica ...
Read moreMorbidity and Mortality of Typhoid Intestinal Perforation Among Children in Sub-Saharan Africa 1995–2019: A Scoping Review
AUTHORS Megan Birkhold, Yacaria Coulibaly, Oumar Coulibaly, Philadelphie Dembélé, Daniel S. Kim, Samba Sow & Kathleen M. Neuzil ABSTRACT Typhoid fever incidence and complications, including intestinal perforation, have declined significantly ...
Read moreDifferentially Regulated Promoters for Antigen Expression in Salmonella Vaccine Strains
AUTHORS Miloš Stojanov, Hervé Besançon, Tiia Snäkä, Denise Nardelli-Haefliger, Roy Curtiss 3rd, David Baud ABSTRACT In most attenuated Salmonella enterica vaccines, heterologous antigens are expressed under the control of strong inducible promoters to ...
Read moreSalmonella Typhoid Toxin PltB Subunit and Its Non-typhoidal Salmonella Ortholog Confer Differential Host Adaptation and Virulence
AUTHORS Sohyoung Lee, Yi-An Yang, Shawn K Milano, Tri Nguyen, Changhwan Ahn, Ji Hyun Sim, Andrew J Thompson, Eric C Hillpot, Gyeongshik Yoo, James C Paulson, Jeongmin Song ABSTRACT Typhoidal and non-typhoidal Salmonelleae (NTS) cause typhoid fever and gastroenteritis, respectively, ...
Read moreHyperexpression of type III secretion system of Salmonella Typhi linked to a higher cytotoxic effect to monocyte-derived macrophages by activating inflammasome
AUTHORS Hsin-Hung Lin, Hsiu-Ling Chen, Rajendra Prasad Janapatla, Chyi-Liang Chen, Cheng-Hsun Chiu ABSTRACT Inflammasome activation is an important host response to infectious diseases, but the difference in inflammasome activation between typhoid fever and ...
Read moreSalmonella Persistence and Host Immunity Is Dictated by the Anatomical Microenvironment
AUTHORS Jonathan R Kurtz, Wildaliz Nieves, David Bauer, Kate Israel, Haley E Adcox, John S Gunn, Lisa A Morici, James B McLachlan ABSTRACT The intracellular bacterial pathogen Salmonella is able to evade the immune system and persist ...
Read moreEtiologic Agents of Fever of Unknown Origin Among Patients Attending Mnazi Mmoja Hospital, Zanzibar
AUTHORS Mohamed Ali Ali, Okafor Chukwuma James, Ahmed Abade Mohamed, Agricola Joachim, Marcelina Mubi, Oghenekaro Omodior ABSTRACT Background: Fever of unknown origin (FUO) remains an important public health problem. With malaria transmission declining in some ...
Read moreNew Roles for Two-Component System Response Regulators of Salmonella enterica Serovar Typhi during Host Cell Interactions
AUTHORS Claudie Murret-Labarthe, Maud Kerhoas, Karine Dufresne, France Daigle ABSTRACT In order to survive external stresses, bacteria need to adapt quickly to changes in their environment. One adaptive mechanism is to coordinate ...
Read moreDrug Repurposing Approach to Target FtsZ Cell Division Protein From Salmonella Typhi
AUTHORS Farah Naz, Muneera Mashkoor, Priyanka Sharma, Md Anzarul Haque, Arti Kapil, Manoj Kumar, Punit Kaur, Abdul S Ethayathulla ABSTRACT Drug repurposing is an efficient alternative approach to counter the increasing drug-resistant pathogens to treat infectious diseases. ...
Read moreAntimicrobial Resistance in Nontyphoidal Salmonella Isolates From Human and Swine Sources in Brazil: A Systematic Review of the Past Three Decades
AUTHORS Grazielle Lima Rodrigues, Pedro Panzenhagen, Rafaela Gomes Ferrari, Vania Margaret Flosi Paschoalin, Carlos Adam Conte-Junior ABSTRACT Salmonella are the leading cause of foodborne illnesses worldwide. The widespread use of antimicrobials as prophylactic, therapeutic, ...
Read moreDesigning a typhoid environmental surveillance study: A simulation model for optimum sampling site allocation
AUTHORS Yuke Wang, Christine L. Moe, Shanta Dutta, Ashutosh Wadhwa, Suman Kanungo, Wolfgang Mairinger, Yichuan Zhao, Yi Jiang, Peter FM.Teunis ABSTRACT Environmental surveillance can be used for monitoring enteric disease ...
Read moreAn Alternative Penicillin-Binding Protein Involved in Salmonella Relapses Following Ceftriaxone Therapy
AUTHORS Sónia Castanheira, David López-Escarpa, M Graciela Pucciarelli, Juan J Cestero, Fernando Baquero, Francisco García-Del Portillo ABSTRACT Background: Salmonella causes intracellular infections in humans. Besides quinolones, third generation cephalosporins are ...
Read moreConsultation on the feasibility and ethics of specific, probable Controlled Human Infection Model study scenarios in India: A report
AUTHORS Manjulika Vaz, Olinda Timms, Anuradha Rose, Abi Manesh, Anant Bhan ABSTRACT On March 6, 2019, a workshop was held as part of a larger public consultation exercise to evaluate ...
Read moreOutbreak of acute undifferentiated febrile illness in Kathmandu, Nepal: clinical and epidemiological investigation
AUTHORS Sunil Pokharel, Manan Karki, Bhim Acharya, Baburam Marasini, Amit Arjyal ABSTRACT Background: Outbreaks of acute undifferentiated febrile illness (AUFI) are common in Nepal, but the exact etiology or risk ...
Read moreRecombinant protein production and purification of SiiD, SiiE and SiiF – Components of the SPI4-encoded type I secretion system from Salmonella Typhimurium
AUTHORS Stefan Klingl, Sina Kordes, Benedikt Schmid, Roman G. Gerlach, Michael Hensel, Yves A. Muller ABSTRACT In humans, Salmonella enterica infections are responsible for a plethora of medical conditions. These ...
Read moreThe first imported case of extensively drug-resistant Salmonella enterica serotype Typhi infection in Taiwan and the antimicrobial therapy
AUTHORS Po-Yu Liu, Kung-Ching Wang, Yu-Ping Hong, Bo-Han Chen, Zhi-Yuan Shi, Chien-Shun Chiou ABSTRACT The first imported case of XDR typhoid fever in Taiwan contracted with a bacterial strain, which ...
Read moreA Decision Support System for Multi-Target Disease Diagnosis: A Bioinformatics Approach
AUTHORS Femi Emmanuel Ayo, Joseph Bamidele Awotunde, Roseline Oluwaseun Ogundokun, Sakinat Oluwabukonla Folorunso, Adebola Olayinka Adekunle ABSTRACT Malaria and typhoid fever are revered for their ability to individually or jointly ...
Read moreDisease burden from foodborne illnesses in Taiwan, 2012–2015
AUTHORS Ying-Ho Lai, Yu-An Chung, Yun-Chun Wu, Chi-Tai Fang, Pei-Jer Chen ABSTRACT Background/Purpose: Foodborne disease is a global health problem. We aim to provide the first national estimate on disease ...
Read moreDevelopment of a Specific and Sensitive HPAEC-PAD Method for Quantification of Vi Polysaccharide Applicable to other Polysaccharides Containing Amino Uronic Acids
AUTHORS Carlo Giannelli, Maria Michelina Raso, Elena Palmieri, Antonia De Felice, Federico Pippi, Francesca Micoli ABSTRACT Typhoid fever is a major cause of morbidity and mortality in developing countries. Vaccines ...
Read moreReviving the “Moore swab”: a classic environmental surveillance tool involving filtration of flowing surface water and sewage water to recover typhoidal Salmonella
AUTHORS Michael J. Sikorski, Myron M. Levine ABSTRACT The Moore swab is a classic environmental surveillance tool whereby a gauze pad tied with string is suspended in flowing water or ...
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