New data from research on the disease burden of typhoid and ways to prevent, treat, and control the disease are crucial in the fight to take on typhoid. See the latest key publications or filter and search the full list of typhoid publications below.
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Identification of Novel Vaccine Candidate Against Salmonella Enterica Serovar Typhi by Reverse Vaccinology Method and Evaluation of Its Immunization
AUTHORS Ehsan Esmailnia, Jafar Amani, Seyed Latif Mousavi Gargari ABSTRACT Salmonella enterica serovar Typhi (S. Typhi) is an essential enteric fever causing bacterium worldwide. Due to the emergence of multidrug-resistant strains, urgently ...
Read moreEvaluation of a Standardised Vi Poly-L-Lysine ELISA for Serology of Vi Capsular Polysaccharide Antibodies
AUTHORS Peter Rigsby, Emma Beamish, Jason Hockley, Eleanor Atkinson, Krisztina Hitri, Elizabeth Jones, Jae Seung Yang, Firdausi Qadri, Novilia S Bachtiar, Sean C Elias, Akshay Goel , Ravipratapnarayan Mishra, Raju Dugyala, Marcela F Pasetti, James E Meiring, Maurice Mbewe, Melita A Gordon, Andrew ...
Read moreSalmonella Typhi and Paratyphi A Infections in Cambodian Children, 2012 – 2016
AUTHORS Chheng Kheng, Vorlark Meas, Sotheavy Pen, Poda Sar, Paul Turner ABSTRACT Objectives: Enteric fever remains an important diagnostic and treatment challenge in febrile children living in the tropics. In the context of a ...
Read moreUse of Typhoid Vi-Polysaccharide Vaccine as a Vaccine Probe to Delineate Clinical Criteria for Typhoid Fever
AUTHORS Taufiqul Islam, Justin Im, Faisal Ahmmed, Deok Ryun Kim, Ashraful Islam Khan, Khalequ Zaman, Mohammad Ali, Florian Marks, Firdausi Qadri, Jerome Kim, John D Clemens ABSTRACT Blood cultures (BCs) detect an estimated 50% of typhoid fever cases. There is ...
Read moreSyntheses of Salmonella Paratyphi A Associated Oligosaccharide Antigens and Development Towards Anti-Paratyphoid Fever Vaccines
AUTHORS Debashis Dhara, Scott M Baliban, Chang-Xin Huo, Zahra Rashidijahanabad, Khandra T Sears, Setare Tahmasebi Nick, Anup Kumar Misra, Sharon M Tennant, Xuefei Huang ABSTRACT With the emergence of multidrug resistant Salmonella strains, the development of anti- Salmonella ...
Read moreSpinal Epidural Abscess Caused by Non-Typhoidal Salmonella: A Case Report and Literature Review
AUTHORS Nobuyasu Hirai, Kei Kasahara, Shingo Yoshihara, Tomoko Nishimura, Yoshihiko Ogawa, Taku Ogawa, Naokuni Hishiya, Yuki Suzuki, Hisakazu Yano, Masahide Yoshikawa ABSTRACT Non-typhoidal Salmonellae are Gram negative bacilli commonly causing self-limiting gastroenteritis, representing a public health issue particularly in ...
Read moreThe Application Research of xTAG GPP Multiplex PCR in the Diagnosis of Persistent and Chronic Diarrhea in Children
AUTHORS Chunli Wang, Xiaoying Zhou, Mengshu Zhu, Hanjun Yin, Jiamei Tang, Yan Huang, Bixia Zheng, Yu Jin, Zhifeng Liu ABSTRACT Background: Persistent and chronic diarrhea is difficult to treat, and infection is still the main cause. In this ...
Read moreEtiology of Diarrhea Requiring Hospitalization in Bangladesh by Quantitative PCR, 2014-2018
AUTHORS Mami Taniuchi, Kamrul Islam, Md Abu Sayeed, James A Platts-Mills, Md Taufiqul Islam, Md Imam Ul Khabir, Muntasir Rahman, Zahid Hasan Khan, Yasmin Ara Begum, Farhana Khanam, Ashraful Islam Khan, Jie Liu, Eric R Houpt, Firdausi Qadri ABSTRACT Background: Diarrhea remains a ...
Read moreWhole-Genome Sequences of Salmonella Isolates From an Ecological Wastewater Treatment System
AUTHORS Charles J Connolly, Laura Kaminsky, Gabriella N Pinto, Priscilla C Sinclair, Gyasu Bajracharya, Runan Yan, Erin M Nawrocki, Edward G Dudley, Jasna Kovac ABSTRACT Twenty-seven Salmonella isolates were collected from four locations within an ecological wastewater treatment ...
Read moreAccessibility of O Antigens Shared Between Salmonella Serovars Determines Antibody-Mediated Cross-Protection
AUTHORS Anees Ahmed, Ajay Suresh Akhade, Ayub Qadri ABSTRACT Pathogenic Salmonella serovars produce clinical manifestations ranging from systemic infection typhoid to invasive nontyphoidal Salmonella disease in humans. These serovars share a high ...
Read moreFactors Associated With Occurrence of Salmonellosis Among Children Living in Mukuru Slum, an Urban Informal Settlement in Kenya
AUTHORS Cecilia Mbae, Moses Mwangi, Naomi Gitau, Tabitha Irungu, Fidelis Muendo, Zilla Wakio, Ruth Wambui, Susan Kavai, Robert Onsare, Celestine Wairimu, Ronald Ngetich, Frida Njeru, Sandra Van Puyvelde, John Clemens, Gordon Dougan, Samuel Kariuki ABSTRACT Background: In Kenya, typhoid fever and invasive non-typhoidal salmonellosis present ...
Read moreVaccines Against Gastroenteritis, Current Progress and Challenges
AUTHORS Hyesuk Seo, Qiangde Duan, Weiping Zhang ABSTRACT Enteric viral and bacterial infections continue to be a leading cause of mortality and morbidity in young children in low-income and middle-income countries, the ...
Read moreEffect of rpoE on the Non-coding RNA Expression Profiles of Salmonella Enterica Serovar Typhi Under the Stress of Ampicillin
AUTHORS Biying Zhang, Yinyin Fan, Min Wang, Jingnan Lv, Haifang Zhang, Lanyun Sun, Hong Du ABSTRACT Gene transcription in bacteria is mainly triggered by sigma factors (σ factors), such as rpoE. Bacterial ncRNAs are key players ...
Read moreIn Vitro and in Vivo Anti-Salmonella Properties of Hydroethanolic Extract of Detarium Microcarpum Guill. & Perr. (Leguminosae) Root Bark and LC-MS-based Phytochemical Analysis
AUTHORS Michel Arnaud Mbock, William Feudjou Fouatio, Raceline Gounoue Kamkumo, Patrick Valère Tsouh Fokou, Florence Ngueguim Tsofack, Paul-Keilah Lunga, Jean Justin Essia Ngang, Onana Boyomo, Augustin Ephrem Nkengfack, Bruno Lenta Ndjakou, Norbert Sewald, Fabrice Fekam Boyom, Theophile Dimo ABSTRACT Ethnopharmacological relevance: ...
Read moreTyphoid Outbreaks, 1989-2018: Implications for Prevention and Control
AUTHORS Grace D Appiah, Alexandria Chung, Adwoa D Bentsi-Enchill, Sunkyung Kim, John A Crump, Vittal Mogasale, Rachael Pellegrino, Rachel B Slayton, Eric D Mintz ABSTRACT Typhoid fever remains an important public health problem in low- and middle-income countries, ...
Read moreMass Azithromycin Administration: Considerations in an Increasingly Resistant World
AUTHORS Yogesh Hooda, Arif M Tanmoy, Mohammad Saiful Islam Sajib, Senjuti Saha ABSTRACT SUMMARY Recent studies have shown that mass administration of azithromycin in some areas can lead to reduction in childhood mortality, ...
Read moreA Whole-Genome Screen Identifies Salmonella Enterica Serovar Typhi Genes Involved in Fluoroquinolone Susceptibility
AUTHORS A Keith Turner, Sabine E Eckert, Daniel J Turner, Muhammud Yasir, Mark A Webber, Ian G Charles, Julian Parkhill, John Wain ABSTRACT Objectives: A whole-genome screen at sub-gene resolution was performed to identify candidate loci that ...
Read moreEvaluation of a Rapid Point-of-Care Multiplex Immunochromatographic Assay for the Diagnosis of Enteric Fever
AUTHORS Shailendra Kumar, Ariana Nodoushani, Farhana Khanam, Alyssa T DeCruz, Paul Lambotte, Robert Scott, Isaac I Bogoch, Krista Vaidya, Stephen B Calderwood, Taufiqur R Bhuiyan, Javan Esfandiari, Edward T Ryan, Firdausi Qadri, Jason R Andrews, Richelle C Charles ABSTRACT There is a critical need ...
Read moreLaparoscopic Management of Gall Bladder Perforation Secondary to Typhoid-Induced Acalculous Cholecystitis: A Rare Entity
AUTHORS Anupam Goel, Vivek Bindal, Sudhir Kalhan, Parveen Bhatia, Mukund Khetan, Suviraj John ABSTRACT Gall bladder perforation as a sequel of typhoid-induced acalculous cholecystitis is a rare clinical encounter, reported sparsely in literature. Here, we ...
Read moreMolecular and Epidemiologic Analysis of Diarrheal Pathogens in Children With Acute Gastroenteritis in Bangladesh During 2014-2019
AUTHORS Nadim Sharif, Nasir Uddin Nobel, Najmuj Sakib, Syeda Moriam Liza, Shafia Tasnim Khan, Baki Billah, Anowar Khasru Parvez, Aynul Haque, Ali Azam Talukder, Shuvra Kanti Dey ABSTRACT Background: Diarrheal disease is one of the leading causes of childhood ...
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