New data from research on the disease burden of typhoid and ways to prevent, treat, and control the disease are crucial in the fight to take on typhoid. See the latest key publications or filter and search the full list of typhoid publications below.
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Extended spectrum beta-lactamase and fluoroquinolone resistance genes among Escherichia coli and Salmonella isolates from children with diarrhea, Burkina Faso
AUTHORS René Dembélé, Ali Konaté, Oumar Traoré, Wendpoulomdé A D Kaboré, Issiaka Soulama, Assèta Kagambèga, Alfred S Traoré, Nathalie K Guessennd, Awa Aidara-Kane, Amy Gassama-Sow, Nicolas Barro ABSTRACT Background: The emergence and spread of multidrug-resistant gram-negative bacteria (MDR) has become ...
Read morePopulation pharmacokinetics of ciprofloxacin in Pakistani patients suffering from enteric fever
AUTHORS Rabia Saleem, Humaira Majeed Khan, Muhammad Usman, Muhammad Imran Khokhar, Huma Rasheed, Mateen Abbas, Rizwan Rasul Khan, Madiha Zaman, Zunair Maqsood ABSTRACT Background: Ciprofloxacin, a potent carboxy-fluoroquinolone is proved to be effective against some resistant strains of ...
Read moreFailure of CD4 T cell-deficient hosts to control chronic non-typhoidal Salmonella infection leads to exacerbated inflammation, chronic anemia, and altered myelopoiesis
AUTHORS Wendy P. Loomis, Martha A. Delaney, Matthew L. Johnson, Brad T. Cookson ABSTRACT Immunocompromised patients are more susceptible to recurrent non-typhoidal Salmonella (NTS) bacteremia. A key manifestation of HIV infection is the ...
Read moreWhole-genome sequencing to investigate two concurrent outbreaks of Salmonella Enteritidis in South Africa, 2018
AUTHORS Anthony M Smith, Nomsa P Tau, Hlengiwe M Ngomane, Phuti Sekwadi, Ntsieni Ramalwa, Krishna Moodley, Chetna Govind, Shameema Khan, Moherndran Archary, Juno Thomas ABSTRACT Salmonella enterica serotype Enteritidis (Salmonella Enteritidis) is a major cause of foodborne ...
Read moreStructure based drug discovery and in vitro activity testing for DNA gyrase inhibitors of Salmonella enterica serovar Typhi
AUTHORS Priyanka Sharma, Manoj Kumar, Sushila Dahiya, Seema Sood, Bimal Kumar Das, Punit Kaur, Arti Kapil ABSTRACT The emerged resistance in Typhoidal Salmonella has limited the treatment options for typhoid fever. In this scenario, there ...
Read moreCan existing improvements of water, sanitation, and hygiene (WASH) in urban slums reduce the burden of typhoid fever in these settings?
AUTHORS Justin Im, Md Taufiqul Islam, Faisal Ahmmed, Deok Ryun Kim, Ashraful Islam Khan, Khalequ Zaman, Mohammad Ali, Florian Marks, Firdausi Qadri, Jerome Kim, John D Clemens ABSTRACT Background: Sustained investment in water, sanitation and hygiene (WASH) has ...
Read moreGenotoxic Effect of Salmonella Paratyphi A Infection on Human Primary Gallbladder Cells
AUTHORS Ludovico P Sepe, Kimberly Hartl, Amina Iftekhar , Hilmar Berger, Naveen Kumar, Christian Goosmann, Sascha Chopra, Sven Christian Schmidt, Rajendra Kumar Gurumurthy, Thomas F Meyer, Francesco Boccellato ABSTRACT Carcinoma of the gallbladder (GBC) is the most ...
Read moreEtiology, clinical presentation, and outcome of children with fulminant hepatic failure: Experience from a tertiary center in Pakistan
AUTHORS Sidra Talat, Sabeen Abid Khan, Nismat Javed, Munir Iqbal Malik ABSTRACT Objectives: To determine etiologies, clinical presentations and outcomes of children with fulminant hepatic failure in the first liver transplant center of ...
Read moreMolecular Detection of gyrA Gene in Salmonella enterica serovar Typhi Isolated from Typhoid Patients in Baghdad
AUTHORS Khetam Habeeb Rasool, Nadheema Hammood Hussein, Butheina Mahamed Taha ABSTRACT Background and objective: Typhoid fever is endemic in most countries, causing major public health problems with high morbidity and mortality, the ...
Read moreAssociations among Water, Sanitation, and Hygiene, and Food Exposures and Typhoid Fever in Case–Control Studies: A Systematic Review and Meta-Analysis
AUTHORS Sarah Brockett, Marlene K. Wolfe, Asa Hamot, Grace D. Appiah, Eric D. Mintz, Daniele Lantagne ABSTRACT Typhoid fever transmission occurs through ingestion of food or water contaminated with Salmonella ...
Read moreTyphoid Fever in the U.S. Pediatric Population, 1999–2015: Opportunities for Improvement
AUTHORS Jarred McAteer, MD, Gordana Derado, PhD, Michael Hughes, MPH, Amelia Bhatnagar, BS, Felicita Medalla, MD, Kevin Chatham-Stevens, MD, Grace D Appiah, MD, Eric Mintz, MD ABSTRACT Introduction Typhoid fever ...
Read more50 Years Ago in The Journal of Pediatrics: Drug Sensitivity to Salmonella typhi: Coming Full Circle
AUTHORS Pinky Meena, Piyush Gupta ABSTRACT In 1970, Chawla et al were concerned about the “rampant use” of chloramphenicol for treatment of typhoid fever owing to its serious toxic effects. They studied ...
Read moreDetection of Enteric Viruses and Bacterial Indicators in a Sewage Treatment Center and Shallow Water Bay
AUTHORS Essam M Janahi, Sakina Mustafa, Saba F D Parkar, Humood A Naser, Zaki M Eisa ABSTRACT The incidence of enteric viruses in treated wastewater and their potential release into the environment or use ...
Read moreShort Vi-polysaccharide abrogates T-independent immune response and hyporesponsiveness elicited by long Vi-CRM 197 conjugate vaccine
AUTHORS Francesca Micoli, Stefania P Bjarnarson, Melissa Arcuri, Audur Anna Aradottir Pind, Gudbjorg J Magnusdottir, Francesca Necchi, Roberta Di Benedetto, Martina Carducci, Fabiola Schiavo, Carlo Giannelli, Ivan Pisoni, Laura B Martin, Giuseppe Del Giudice, Calman A MacLennan, Rino Rappuoli, Ingileif Jonsdottir, Allan Saul ABSTRACT Polysaccharide-protein conjugates ...
Read moreGenomic serotyping, clinical manifestations, and antimicrobial resistance of non-typhoidal Salmonella gastroenteritis in hospitalized children in Ho Chi Minh City, Vietnam
AUTHORS Vu Thuy Duong, Hao Chung The, Tran Do Hoang Nhu, Ha Thanh Tuyen, James I Campbell, Pham Van Minh, Hoang Le Phuc, Tran Thi Hong Chau, Nguyen Minh Ngoc, Lu Lan Vi, Alison E Mather, Stephen Baker ABSTRACT Nontyphoidal Salmonella ...
Read moreDetection and Characterization of Salmonella enterica Serotypes by Simple PCR Technologies
AUTHORS Samuel Kariuki, John Kiiru ABSTRACT Polymerase chain reaction (PCR) is a molecular-based technology that has revolutionized diagnostics and characterization of pathogens, and thus affecting how we understand disease landscape. This ...
Read moreInvestigating the meat pathway as a source of human nontyphoidal Salmonella bloodstream infections and diarrhea in East Africa
AUTHORS John A Crump, Kate M Thomas, Jackie Benschop, Matthew A Knox, David A Wilkinson, Anne C Midwinter, Peninah Munyua, John B Ochieng, Godfrey M Bigogo, Jennifer R Verani, Marc-Alain Widdowson, Gerard Prinsen, Sarah Cleaveland, Esron D Karimuribo, Rudovick R Kazwala, Blandina T Mmbaga, Emanuel S ...
Read moreSelf-reported diseases and their associated risk factors among camp-dwelling conflict-affected internally displaced populations in Nigeria
AUTHORS Winifred Ekezie, Puja Myles, Rachael L Murray, Manpreet Bains, Stephen Timmons, Catherine Pritchard ABSTRACT Background Conflict in Nigeria displaced millions of people, and some settled in camp-like locations within the country. Evidence on the ...
Read moreElimination of typhoid: Possibility or pipe dream?
AUTHORS Rachael Purcell, Andrew J Pollard ABSTRACT The elimination of typhoid would have a substantial impact on the health of millions of people living in South and Southeast Asia and ...
Read moreDrug resistance in Salmonella Typhi: implications for South Asia and travel
AUTHORS Sneha Radha, Malathi Murugesan, Priscilla Rupali ABSTRACT Purpose of review: Recent attempts at mapping Typhoid epidemiology have revealed an enormous burden of disease in developing countries. Countries hitherto believed to have ...
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