Stories of Typhoid: Asim
Meet Asim. In his low-income urban neighborhood in Pakistan, it can seem as if the one thing more widespread than typhoid is misinformation about typhoid. Crucial information on the prevention of the disease through handwashing, drinking clean water or receiving a vaccination is often missing in places where typhoid is endemic, leaving kids like Asim at high risk of suffering unnecessarily from preventable diseases.
Until recently, Asim didn’t know much more about typhoid than any other kid from his neighborhood. He didn’t know that typhoid is transmitted through contaminated food and water, or that some street vendors can’t guarantee the safety of the food they’re selling. Asim didn’t know that every time he bought his favorite snacks from the street vendor near his school, he ran the risk of contracting typhoid. But one day that risk caught up with him. Read more about his story.
Conference Updates
The 10th International Conference on Typhoid and Other Invasive Salmonelloses is fast approaching. Don’t forget to register before the March 6 deadline.
The conference program overview is now up on our website, where you can also find important conference dates and travel information. We hope to see you all April 4-6, 2017, in Uganda.
From the Blog
- Looking Back at 2016 – As the past year has come to a close, our team at the Coalition against Typhoid would like to take a moment to reflect on this busy year
- Recurring Typhoid Nightmare in Zimbabwe – After struggling with outbreaks for more than a year, Zimbabwe is facing yet another deadly wave of typhoid as it begins the new year
Outbreak Watch
- India – Typhoid cases in Ahmedabad rose from 2,342 in 2015 to 3,016 in 2016. Suspected Salmonella bacteria in the river near Mudumalai has killed cattle and elephants, and may threaten people
- Malaysia – An increase in typhoid cases and one death in Tawau is being monitored carefully
- Nigeria – The crowded conditions and open defecation in refugee camps raises fears of diseases like typhoid
- Syria – A severe water shortage in Syria is raising fears of diseases like typhoid and cholera
- Zimbabwe – An outbreak of typhoid in Zimbabwe has sickened over 2,000 people and killed nine. Most of these cases of typhoid are centered around the capital city of Harare, where water all over the city is contaminated. However, cases have also appeared in Masvingo, Mutare, and Hurungwe. The Zimbabwe Standard shares the impact of typhoid on one patient in Harare
Publications
Featured: Typhoid Fever Surveillance in Africa Project
- Typhoid in Africa and vaccine deployment – Lancet Global Health
- Incidence of invasive salmonella disease in sub-Saharan Africa: a multicentre population-based surveillance study – Lancet Global Health
Case Report/Clinical Outcome
- Frosted Branch Angiitis in a Patient with Typhoid Fever – Ocular Immunology and Inflammation
- Typhoid-associated acute kidney injury masquerading as a relapse of Takayasu arteritis – Saudi Journal of Kidney Diseases and Transplantation
Diagnostics and Treatment
- Typhoid Perforation: Post-operative Intensive Care Unit Care and Outcome – African Journal of Paediatric Surgery
- Promising Effects of Chinese Traditional Treatment for Child Typhoid Complicated by Myocarditis – Experimental and Therapeutic Medicine
- Blood culture-PCR to optimise typhoid fever diagnoses after controlled human infection identifies frequent asymptomatic cases and evidence of primary bacteraemia – The Journal of Infection
Epidemiology
- A Large and Persistent Outbreak of Typhoid Fever Caused by Consuming Contaminated Water and Street-Vended Beverages: Kampala, Uganda, January-June 2015 – BMC Public Health
- Poverty-related Diseases (PRDs): Unravelling Complexities in Disease Responses in Cameroon – Tropical Medicine and Health
- Application of landscape epidemiology to assess potential public health risk due to poor sanitation – Journal of Environmental Management
Genomics
- The Cytolethal Distending Toxin Produced by Nontyphoidal Salmonella Serotypes Javiana, Montevideo, Oranienburg, and Mississippi Induces DNA Damage in a Manner Similar to That of Serotype Typhi – mBio
Vaccines
- Whole Genome Sequence Analysis of Salmonella Typhi Isolated in Thailand Before and After the Introduction of a National Immunization Program – PLoS Neglected Tropical Diseases
- Evaluation of the clinical and microbiological response to Salmonella Paratyphi A infection in the first paratyphoid human challenge model – Clinical Infectious Diseases
- Salmonella Typhi Lipopolysaccharide O-antigen Modifications Impact on Serum Resistance and Antibody Recognition – Infection and Immunity
- Modeling the Potential for Vaccination to Diminish the Burden of Invasive Non-typhoidal Salmonella Disease in Young Children in Mali, West Africa – PLoS Neglected Tropical Diseases
Water, Sanitation and Hygiene
- Food Safety Knowledge, Attitudes and Practices of Institutional Food-Handlers in Ghana – BMC Public Health
To contribute to the Coalition Against Typhoid Knowledge Exchange Newsletter, contact us at cat@sabin.org. Like us on Facebook and Twitter to stay connected.
