Outbreak Watch
- 14 cases of typhoid fever were reported in Tailevu province, Fiji, at the end of March. More cases were reported throughout Fiji in April; the increase in typhoid was linked to the damage caused by tropical cyclone Winston, which struck the country in late February.
- Typhoid claimed 6 lives in Masaka district, Uganda, in early April.
- 18 cases of typhoid fever were confirmed in Mchinji district, Malawi, in mid-April, prompting local hospitals to hold educational meetings on hygiene practices.
Publications
Diagnostics and Treatments
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Optimization of Salmonella Typhi biofilm assay on polypropylene microtiter plates using response surface methodology – Biofouling: The Journal of Bioadhesion and Biofilm Research
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Comparison of the Performance of the TPTest, Tubex, Tyhpidot and Widal Immunodiagnostic Assays and Blood Cultures in Detecting Patients with Typhoid Fever in Bangladesh, Including Using a Bayesian Latent Class Modeling Approach – PLoS Neglected Tropical Diseases
Epidemiology and Surveillance
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Trends of reported foodborne diseases at the Ridge Hospital, Accra, Ghana: a retrospective review of routine data from 2009-2013 – BMC Infectious Diseases
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Enteric Fever in a Multicultural Canadian Tertiary Care Pediatric Setting: A 28-Year Review – Journal of the Pediatric Infectious Disease Society
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Changing Patterns of Disease and Mortality at the Children’s Hospital, Accra: Are Infections Rising? – PLoS One
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The Aetiologies and Impact of Fever in Pregnant Inpatients in Vientiane, Laos – PLoS Neglected Tropical Diseases
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The Burden of Typhoid and Paratyphoid in India: Systematic Review and Meta-analysis – PLoS Neglected Tropical Diseases
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Changing Patterns in Enteric Fever Incidence and Increasing Antibiotic Resistance of Enteric Fever Isolates in the United States, 2008-2012 – Clinical Infectious Diseases
Genomics and Host Susceptibility
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Functional Activity of Antibodies Directed towards Flagellin Proteins of Non-Typhoidal Salmonella – PLoS One
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Genotyping of Salmonella Typhi using 8-loci multi locus VNTR analysis – Gut Pathogens
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The Typhoid Toxin Promotes Host Survival and the Establishment of a Persistent Asymptomatic Infection – PLoS Pathogens
Vaccines
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Status of paratyphoid fever vaccine research and development – Vaccine
Events
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April 24-30 – CaT celebrated World Immunization Week on Twitter and Facebook, using #WorldImmunizationWeek to highlight the importance of vaccination to typhoid prevention.
Photo Credit: Yannis Guibinga